Sugi Predict

Sugi Predict / Compounds / SCHEMBL83480

SCHEMBL83480

SCHEMBL83480

O=S(=O)(O)C1(c2ccccc2)N=c2ccccc2=N1

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 1/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.37
▸ ALDH1A1 P00352 1/20 0.32
▸ HSD17B10 Q99714 1/20 0.32
▸ TDP1 Q9NUW8 1/20 0.32
▸ BACE1 P56817 1/20 0.32
▸ BACE2 Q9Y5Z0 1/20 0.32
▸ LMNA P02545 1/20 0.32
▸ GLA P06280 1/20 0.32
▸ THRB P10828 1/20 0.32
▸ CYP2C9 P11712 1/20 0.32
▸ BLM P54132 1/20 0.32
▸ PMP22 Q01453 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ SRC P12931 1/20 0.31
▸ AKR1C1 Q04828 1/20 0.31
▸ POLB P06746 1/20 0.30
▸ GPR55 Q9Y2T6 1/20 0.30
▸ HTR6 P50406 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9289134 0.82 TTR (0.33) TSHRSMN1; SMN2
SCHEMBL149345 0.71 TSHR (0.34) TSHRSMN1; SMN2ALDH1A1HSD17B10TDP1
SCHEMBL989262 0.71 TSHR (0.34) TSHRSMN1; SMN2ALDH1A1HSD17B10TDP1
SCHEMBL9394273 0.71 TSHR (0.31) TSHRSMN1; SMN2
SCHEMBL9818519 0.69 SMN1; SMN2 (0.32) TSHRSMN1; SMN2KMT2A
SCHEMBL1284435 0.67 KMT2A (0.32) TSHRTDP1BACE1BACE2LMNA
SCHEMBL6519735 0.67 TSHR (0.31) TSHRSMN1; SMN2ALDH1A1LMNA
SCHEMBL11264366 0.66 LMNA (0.38) BACE1BACE2LMNAGLATHRB
SCHEMBL6519744 0.64 TSHR (0.32) TSHRSMN1; SMN2ALDH1A1TDP1LMNA
SCHEMBL3969182 0.64 BACE1 (0.34) SMN1; SMN2BACE1BACE2LMNAGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1397 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4676433-A1 LIQUID UV FILTER CONCENTRATE Symrise AG (DE) 2026-01-14 — — EP claimed
EP-4676428-A1 LIQUID UV FILTER COMPOSITION CONTAINING DIOLS Symrise AG (DE) 2026-01-14 — — EP claimed
US-11723850-B2 Liquid and transparent blend of UV filters Symrise, AG (DE) 2023-08-15 — — US claimed
US-11559557-B2 Medicament comprising ginger root CO2 extract SYMRISE AG (DE) 2023-01-24 — — US claimed
US-20220354772-A1 BLEND OF BEESWAX AND A LACTYLATE ESTER SYMRISE AG (DE) 2022-11-10 — — US claimed
EP-3993767-A1 BLEND OF BEESWAX AND A LACTYLATE ESTER Symrise AG (DE) 2022-05-11 — — EP claimed
US-20220071872-A1 A LIQUID AND TRANSPARENT BLEND OF UV FILTERS SYMRISE AG (DE) 2022-03-10 — — US claimed
CN-114126579-A Mixture of beeswax and lactoyl lactate 西姆莱斯股份公司 2022-03-01 — — CN claimed
EP-3873622-A1 A LIQUID AND TRANSPARENT BLEND OF UV FILTERS Symrise AG (DE) 2021-09-08 — — EP claimed
CN-113164792-A Liquid transparent mixtures of UV filters 西姆莱斯股份公司 2021-07-23 — — CN claimed
WO-2002038537-A1 NOVEL INDANYLIDENE COMPOUNDS HAARMANN & REIMER GMBH (DE) 2002-05-16 — — WO claimed
US-20020055532-A1 UV-B filter MERCK PATENT GESELLSCHAFT (DE) 2002-05-09 — — US claimed
US-20020016349-A1 UV-B filters MERCK PATENT GESELLSCHAFT (DE) 2002-02-07 — — US claimed
EP-1167358-A1 2-Phenylbenzimidazole sulphonic acids as UV-B filters MERCK PATENT GmbH (DE) 2002-01-02 — — EP claimed
WO-2001093822-A2 AQUEOUS DISPERSIONS OF NANO-PARTICULATE UV-FILTERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-12-13 — — WO claimed
US-6153174-A Cosmetic compositions comprising a combination of UV absorbers BASF AKTIENGESELLSCHAFT (DE) 2000-11-28 — — US claimed
US-6123929-A A COSMETIC SUNSCREEN COMPRISES IN AN AQUEOUS PHASE A 2-PHENYLBENZIMIDAZOLE SULFONIC ACID OR SALT AND A FATTY PHASE CONTAINING A LINEAR OR CYCLIC MODIFIED POLYSILOXANE ROCHE VITAMINS INC. (US) 2000-09-26 — — US claimed
EP-0979645-A1 Light screening composition containing a polysiloxane type UV-B screening agent and a benzimidazol type UV-B screening agent F. HOFFMANN-LA ROCHE AG (CH) 2000-02-16 — — EP claimed
CN-1242190-A Light screening composition containing polysiloxane type UV-B screening agent and benzimidazol type UV-B screening agent HOFFMANN LA ROCHE (CH) 2000-01-26 — — CN claimed
EP-0838214-A2 Cosmetic compositions containing a combination of UV-absorbers including a triazine derivative BASF AKTIENGESELLSCHAFT (DE) 1998-04-29 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11559557-B2 Medicament comprising ginger root CO2 extract CRY1, GRK1, GPER1 TSHR 2117/4885SMN1; SMN2 4852/4885ALDH1A1 897/4885
US-20020055532-A1 UV-B filter CBR1, UQCRB, H1-0 TSHR 1110/4885SMN1; SMN2 3751/4885ALDH1A1 307/4885
US-20220354772-A1 BLEND OF BEESWAX AND A LACTYLATE ESTER LAGE3, CRY1, BROX TSHR 4285/4885SMN1; SMN2 3251/4885ALDH1A1 2226/4885
US-20020016349-A1 UV-B filters CBR1, H1-0, CYP1B1 TSHR 1108/4885SMN1; SMN2 3612/4885ALDH1A1 289/4885
US-11723850-B2 Liquid and transparent blend of UV filters F2, F12, F10 TSHR 3544/4885SMN1; SMN2 4515/4885ALDH1A1 594/4885
US-20220071872-A1 A LIQUID AND TRANSPARENT BLEND OF UV FILTERS F2, F12, TYR TSHR 3582/4885SMN1; SMN2 4549/4885ALDH1A1 811/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.