Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL989262 | 0.69 | TSHR (0.34) | TSHRSMN1; SMN2KDM4ELMNAMAPT | |
| SCHEMBL149345 | 0.69 | TSHR (0.34) | TSHRSMN1; SMN2KDM4ELMNAMAPT | |
| SCHEMBL6519744 | 0.67 | TSHR (0.32) | TSHRSMN1; SMN2KDM4ELMNAMAPT | |
| SCHEMBL83480 | 0.67 | TSHR (0.37) | TSHRSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL9394273 | 0.65 | TSHR (0.31) | TSHRSMN1; SMN2 | |
| SCHEMBL3967439 | 0.64 | KDM4E (0.32) | KDM4ELMNAMAPTHCRTR1 | |
| SCHEMBL6689571 | 0.63 | LMNA (0.35) | TSHRSMN1; SMN2KDM4ELMNAMAPT | |
| SCHEMBL9270285 | 0.63 | — | — | |
| 1,2-Dichlorobenzene SCHEMBL28623362 | 0.60 | TSHR (0.56) | TSHRSMN1; SMN2KDM4ELMNAALDH1A1 | |
| 1,2-Dichlorobenzene SCHEMBL28859926 | 0.59 | TSHR (0.62) | TSHRSMN1; SMN2KDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051655-B1 | METHODS AND APPARATUS FOR ACCELERATED ORTHOKERATOLOGY | ISTA PHARMACEUTICALS INC (US) | 2005-09-28 | — | — | EP | disclosed |
| EP-1051655-A4 | METHODS AND APPARATUS FOR ACCELERATED ORTHOKERATOLOGY | ISTA PHARMACEUTICALS INC (US) | 2003-03-19 | — | — | EP | disclosed |
| US-20010016731-A1 | Methods and apparatus for accelerated orthokeratology | DEVORE DALE (US) | 2001-08-23 | — | — | US | disclosed |
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| US-6161544-A | Methods for accelerated orthokeratology | KERATOFORM, INC. (US) | 2000-12-19 | — | — | US | disclosed |
| EP-1051655-A1 | METHODS AND APPARATUS FOR ACCELERATED ORTHOKERATOLOGY | Ista Pharmaceuticals, Inc. (US) | 2000-11-15 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |
| WO-1999039238-A1 | METHODS AND APPARATUS FOR ACCELERATED ORTHOKERATOLOGY | KERATOFORM, INC. (US) | 1999-08-05 | — | — | WO | disclosed |