Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12651670 | 0.86 | ATM (0.53) | ATMALDH1A1PKMMAPTCA1 | |
| SCHEMBL11101864 | 0.82 | PKM (0.54) | ATMALDH1A1CYP1A2CYP2C19PKM | |
| SCHEMBL11054954 | 0.78 | LMNA (0.54) | ATMALDH1A1CYP1A2CYP2C19PKM | |
| SCHEMBL6688131 | 0.78 | SMN1; SMN2 (0.56) | SMN1; SMN2KMT2ALMNAMEN1 | |
| SCHEMBL10939799 | 0.76 | ATM (0.62) | ATMALDH1A1CYP1A2CYP2C19PKM | |
| SCHEMBL18183958 | 0.76 | ANPEP (0.43) | PKMMAPTSMN1; SMN2KMT2ALMNA | |
| SCHEMBL5480782 | 0.76 | ATM (0.56) | ATMALDH1A1CYP1A2CYP2C19PKM | |
| SCHEMBL8516411 | 0.75 | ATM (0.57) | ATMALDH1A1CYP1A2CYP2C19PKM | |
| SCHEMBL10614877 | 0.75 | ATM (0.60) | ATMALDH1A1CYP1A2CYP2C19PKM | |
| SCHEMBL7532501 | 0.75 | PKM (0.56) | ATMALDH1A1CYP1A2CYP2C19PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004106291-A1 | HALOETHYL UREA COMPOUNDS AND THE USE THEREOF TO ATTENUATE, INHIBIT OR PREVENT CANCER CELL MIGRATION | IMOTEP INC. (CA) | 2004-12-09 | — | — | WO | disclosed |