Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4511398 | 0.79 | HTT (0.44) | LMNANPSR1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL13116656 | 0.75 | SLC18A3 (0.46) | LMNACHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL14350417 | 0.75 | KMT2A (0.46) | LMNACHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL443828 | 0.72 | CHRNB2 (0.53) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL13040180 | 0.71 | HTT (0.43) | LMNANPSR1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL4511389 | 0.71 | HTT (0.46) | LMNANPSR1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL4511390 | 0.71 | HTT (0.46) | LMNANPSR1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL13660513 | 0.70 | CHRNB2 (0.56) | LMNACHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL4522287 | 0.70 | ALDH1A1 (0.48) | LMNAHTTALDH1A1MEN1KMT2A | |
| SCHEMBL2585749 | 0.70 | ALDH1A1 (0.48) | LMNAHTTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004080583-A2 | PROCESS FOR THE PREPARATION OF threo-METHYLPHENIDATE HYDROCHLORIDE | ISP INVESTMENTS INC. (US) | 2004-09-23 | — | — | WO | disclosed |
| WO-2004080959-A2 | PROCESS FOR THE PREPARATION OF DEXMETHYLPHENIDATE HYDROCHLORIDE | ISP INVESTMENTS INC. (US) | 2004-09-23 | — | — | WO | disclosed |