Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6691974 | 0.92 | POLB (0.46) | POLBGAAALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL6693141 | 0.84 | POLB (0.58) | POLBGAAALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL6689868 | 0.81 | EPHX2 (0.35) | POLBGAAALDH1A1KDM4EEPHX2 | |
| SCHEMBL6684519 | 0.80 | HRH3 (0.33) | GAAALDH1A1HTT | |
| SCHEMBL3312644 | 0.79 | ALDH1A1 (0.47) | POLBALDH1A1KDM4EUSP2SMN1; SMN2 | |
| SCHEMBL3305208 | 0.77 | ALDH1A1 (0.53) | POLBALDH1A1USP2SMN1; SMN2HTT | |
| SCHEMBL6691972 | 0.77 | KEAP1 (0.36) | POLBGAAALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL6690289 | 0.76 | KDM4E (0.46) | POLBGAAALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL16233070 | 0.76 | ALDH1A1 (0.38) | GAAALDH1A1KDM4ESMN1; SMN2HTT | |
| SCHEMBL18024017 | 0.76 | KDM4E (0.53) | POLBGAAALDH1A1KDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004069145-A2 | ANTICANCER COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S LABORATORIES LTD. (IN) | 2004-08-19 | — | — | WO | disclosed |