Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.44 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL237654 | 0.84 | SMN1; SMN2 (0.43) | NPC1RAB9ATAS2R14MAPTALDH1A1 | |
| SCHEMBL6692586 | 0.82 | CNR2 (0.42) | NPC1RAB9AMAOBMAPTL3MBTL1 | |
| SCHEMBL6691586 | 0.82 | SMN1; SMN2 (0.45) | NPC1RAB9ATAS2R14KMT2AMEN1 | |
| SCHEMBL7582816 | 0.76 | NPC1 (0.50) | NPC1RAB9AKMT2AMEN1MAOB | |
| SCHEMBL16128966 | 0.74 | HDAC3 (0.43) | NPC1RAB9APOLBGAAKMT2A | |
| SCHEMBL6689766 | 0.72 | ALDH1A1 (0.43) | NPC1RAB9AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8971190 | 0.71 | LTA4H (0.55) | NPC1RAB9APOLBGAATAS2R14 | |
| SCHEMBL28556797 | 0.71 | SMN1; SMN2 (0.38) | NPC1RAB9ATAS2R14MAOBMAPT | |
| SCHEMBL10908525 | 0.70 | HDAC3 (0.59) | KMT2ACES2CES1MAPTHDAC3 | |
| SCHEMBL11116297 | 0.70 | POLB (0.53) | NPC1RAB9APOLBGAATAS2R14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108770-A1 | LOW ODOR CHAIN TRANSFER AGENTS FOR CONTROLLED RADICAL POLYMERIZATION | RENSSELAER POLYTECHNIC INSTITUTE (US) | 2004-12-16 | — | — | WO | disclosed |