Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 4/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28382522 | 0.84 | CYP2C9 (0.50) | CYP2C9CYP2C19NPSR1ALDH1A1USP2 | |
| SCHEMBL27272838 | 0.75 | CYP2C9 (0.43) | CYP2C9CYP2C19NPSR1ALDH1A1USP2 | |
| SCHEMBL9686204 | 0.74 | CYP2C9 (0.52) | CYP2C9CYP2C19NPSR1ALDH1A1USP2 | |
| SCHEMBL24611385 | 0.74 | OPRM1 (0.54) | CYP2C9CYP2C19NPSR1ALDH1A1USP2 | |
| SCHEMBL11580086 | 0.73 | DRD3 (0.36) | CYP2C9CYP2C19NPSR1ALDH1A1USP2 | |
| SCHEMBL7127124 | 0.72 | MAPT (0.34) | MAPT | |
| SCHEMBL10604555 | 0.71 | DRD3 (0.55) | CYP2C9CYP2C19NPSR1ALDH1A1USP2 | |
| SCHEMBL28232120 | 0.71 | CYP2C9 (0.41) | CYP2C9CYP2C19NPSR1ALDH1A1USP2 | |
| SCHEMBL27821113 | 0.70 | OPRM1 (0.43) | CYP2C9CYP2C19NPSR1ALDH1A1USP2 | |
| SCHEMBL11578056 | 0.70 | OPRM1 (0.37) | CYP2C9CYP2C19NPSR1ALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004071481-A1 | MELANOGENESIS INHIBITOR AND SKIN PREPARATION CONTAINING THE SAME | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2004-08-26 | — | — | WO | disclosed |