SCHEMBL28232120

SCHEMBL28232120

CCCCOOC1(c2ccccc2)OO1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 3/20 0.41
CYP2C19 P33261 3/20 0.41
NPSR1 Q6W5P4 2/20 0.41
LTA4H P09960 2/20 0.41
ALDH1A1 P00352 3/20 0.38
USP2 O75604 1/20 0.38
TDP1 Q9NUW8 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
MEN1 O00255 1/20 0.37
RECQL P46063 1/20 0.37
KMT2A Q03164 1/20 0.37
CYP1A2 P05177 1/20 0.36
TSHR P16473 1/20 0.35
OPRM1 P35372 2/20 0.34
OPRL1 P41146 2/20 0.34
MLNR O43193 1/20 0.34
NR1I2 O75469 1/20 0.34
ESR1 P03372 1/20 0.34
NR3C1 P04150 1/20 0.34
PGR P06401 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28382522 0.82 CYP2C9 (0.50) CYP2C9CYP2C19NPSR1LTA4HALDH1A1
SCHEMBL27272838 0.77 CYP2C9 (0.43) CYP2C9CYP2C19NPSR1LTA4HALDH1A1
SCHEMBL6689900 0.71 CYP2C9 (0.47) CYP2C9CYP2C19NPSR1LTA4HALDH1A1
SCHEMBL1550971 0.69 NPSR1 (0.76) CYP2C9CYP2C19NPSR1TDP1L3MBTL1
SCHEMBL6449521 0.66 LTA4H (0.59) CYP2C9CYP2C19LTA4HALDH1A1TDP1
SCHEMBL27530835 0.64 TSHR (0.56) CYP2C9CYP2C19LTA4HALDH1A1TDP1
SCHEMBL9621057 0.64 SIGMAR1 (0.48) LTA4HALDH1A1TDP1L3MBTL1MEN1
SCHEMBL24611385 0.64 OPRM1 (0.54) CYP2C9CYP2C19NPSR1LTA4HALDH1A1
SCHEMBL28432583 0.63 CYP1A2 (0.53) CYP2C9CYP2C19LTA4HTDP1L3MBTL1
SCHEMBL28357819 0.63 LTA4H (0.55) CYP2C9CYP2C19LTA4HALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108473642-A Oxazine compound, composition and cured product DIC株式会社 2018-08-31 CN disclosed
CN-108368069-A Oxazine compound, composition and cured product DIC株式会社 2018-08-03 CN disclosed