Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 8/20 | 0.44 |
| ▸ | CTSL | P07711 | 5/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6692653 | 0.95 | CTSS (0.43) | CTSSCTSLCTSKGRM7 | |
| SCHEMBL6691194 | 0.91 | CTSS (0.41) | CTSSCTSLCTSKGRM7 | |
| SCHEMBL6688775 | 0.91 | CTSS (0.41) | CTSSCTSLCTSKGRM7 | |
| SCHEMBL6687363 | 0.90 | EPHX1 (0.45) | CTSSCTSLCTSKTP53GRM7 | |
| SCHEMBL6694225 | 0.90 | EPHX1 (0.45) | CTSSCTSLCTSKTP53GRM7 | |
| SCHEMBL6690397 | 0.80 | CTSS (0.54) | CTSSCTSLCTSK | |
| SCHEMBL5843693 | 0.80 | CTSS (0.57) | CTSSCTSLCTSK | |
| SCHEMBL5843696 | 0.80 | CTSS (0.57) | CTSSCTSLCTSK | |
| SCHEMBL6690430 | 0.79 | MEN1 (0.45) | CTSSCTSL | |
| SCHEMBL6691227 | 0.78 | CTSS (0.48) | CTSSCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084842-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |