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Sugi Predict / Compounds / SCHEMBL6690220

SCHEMBL6690220

SCHEMBL6690220

CC1[C@H](C(N)=O)OC(=O)N1c1cc(F)c(N2CCS(=N)(=O)CC2)c(F)c1

nearest known ligand 0.43

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ MAOA P21397 1/20 0.43
▸ FADS1 O60427 1/20 0.31
▸ PDE3B Q13370 2/20 0.30
▸ PDE3A Q14432 2/20 0.30
▸ F10 P00742 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3039862 0.83 MAOA (0.42) MAOAFADS1PDE3BPDE3A
SCHEMBL3039863 0.83 MAOA (0.39) MAOAFADS1PDE3BPDE3AF10
SCHEMBL3042127 0.78 MAOA (0.72) MAOAF10
SCHEMBL3043319 0.75 MAOA (0.40) MAOAFADS1PDE3BPDE3AF10
SCHEMBL6691654 0.74 MAOA (0.35) MAOAFADS1
SCHEMBL3035461 0.73 FADS1 (0.37) MAOAFADS1PDE3BPDE3A
SCHEMBL6688290 0.73 MAOA (0.35) MAOAFADS1F10
SCHEMBL3041907 0.72 FADS1 (0.31) MAOAFADS1
SCHEMBL3042118 0.70 MAOA (0.55) MAOAF10
SCHEMBL3041904 0.69 FADS1 (0.31) MAOAFADS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1478629-A1 N-ARYL-2-OXAZOLIDINONE-5-CARBOXAMIDES AND THEIR DERIVATIVES AND THEIR USE AS ANTIBACTERIALS PHARMACIA & UPJOHN COMPANY (US) 2004-11-24 — — EP disclosed
WO-2003072553-A1 N-ARYL-2-OXAZOLIDINONE-5-CARBOXAMIDES AND THEIR DERIVATES AND THEIR USE AS ANTIBACTERIALS PHARMACIA & UPJOHN COMPANY (US) 2003-09-04 — — WO disclosed