Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 5/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6694243 | 0.90 | HRH3 (0.35) | LMNAHRH3 | |
| SCHEMBL6697773 | 0.89 | LMNA (0.35) | LMNACYP1A2CYP2C9CYP2C19CNR2 | |
| SCHEMBL6690587 | 0.84 | ABCB1 (0.40) | LMNA | |
| SCHEMBL6689482 | 0.83 | CYP2C9 (0.35) | LMNACYP1A2CYP2C9CYP2C19CNR2 | |
| SCHEMBL6694321 | 0.79 | CYP1A2 (0.39) | LMNACYP1A2CYP2C9CYP2C19MCHR1 | |
| SCHEMBL6688607 | 0.79 | ALDH1A1 (0.35) | LMNACYP1A2CYP2C9CYP2C19CNR2 | |
| SCHEMBL6693809 | 0.79 | HRH3 (0.38) | LMNAHRH3 | |
| SCHEMBL6690929 | 0.78 | LMNA (0.40) | LMNAHRH3TP53 | |
| SCHEMBL6697903 | 0.77 | CYP1A2 (0.38) | LMNACYP1A2CYP2C9CYP2C19MCHR1 | |
| SCHEMBL6690604 | 0.77 | LMNA (0.39) | LMNAHRH3TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869016-B1 | Pneumatic radial tires | BRIDGESTONE CORP (JP) | 2004-03-03 | — | — | EP | disclosed |
| US-6336486-B1 | Pneumatic radical tire having cap base tread | BRIDGESTONE CORPORATION (JP) | 2002-01-08 | — | — | US | disclosed |
| EP-0869016-A2 | Pneumatic radial tires | Bridgestone Corporation (JP) | 1998-10-07 | — | — | EP | disclosed |