Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 18/20 | 0.46 |
| ▸ | MMP9 | P14780 | 17/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6689685 | 0.93 | MMP2 (0.39) | MMP2MMP9MMP8MMP13 | |
| SCHEMBL728404 | 0.85 | MMP2 (0.53) | MMP2MMP9MMP8MMP13 | |
| SCHEMBL5611211 | 0.82 | MMP2 (0.51) | MMP2MMP9MMP8MMP13 | |
| SCHEMBL2532335 | 0.81 | MMP2 (0.67) | MMP2MMP9MMP8MMP13 | |
| SCHEMBL728143 | 0.75 | MMP2 (0.57) | MMP2MMP9MMP8MMP13 | |
| SCHEMBL6449006 | 0.72 | MMP2 (0.53) | MMP2MMP9MMP8MMP13 | |
| SCHEMBL6442962 | 0.72 | MMP2 (0.55) | MMP2MMP9MMP8MMP13 | |
| SCHEMBL6462509 | 0.71 | MMP2 (0.60) | MMP2MMP9MMP8MMP13 | |
| SCHEMBL6443590 | 0.71 | MMP2 (0.51) | MMP2MMP9MMP8MMP13 | |
| SCHEMBL6445502 | 0.69 | MMP2 (0.56) | MMP2MMP9MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084903-A1 | USE OF A TRIOXOPYRIMIDINE FOR THE TREATMENT AND PREVENTION OF OCULAR PATHOLOGIC ANGIOGENESIS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-10-07 | — | — | WO | claimed |