Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 7/20 | 0.68 |
| ▸ | PDGFRA | P16234 | 12/20 | 0.68 |
| ▸ | KDR | P35968 | 8/20 | 0.68 |
| ▸ | KIT | P10721 | 3/20 | 0.67 |
| ▸ | AXL | P30530 | 1/20 | 0.62 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1877252 | 0.91 | PDGFRA (0.70) | METPDGFRAKDRKITAXL | |
| SCHEMBL1877070 | 0.90 | PDGFRA (0.84) | METPDGFRAKDRKITAXL | |
| SCHEMBL21301531 | 0.87 | MET (0.85) | METPDGFRAKDRKITAXL | |
| SCHEMBL31324673 | 0.87 | MET (0.85) | METPDGFRAKDRKITAXL | |
| SCHEMBL1879723 | 0.86 | PDGFRA (0.65) | METPDGFRAKDRKITAXL | |
| SCHEMBL20525577 | 0.86 | PDGFRA (0.66) | METPDGFRAKDRKITAXL | |
| SCHEMBL22089673 | 0.85 | PDGFRA (0.74) | METPDGFRAKDRKITAXL | |
| SCHEMBL1879043 | 0.85 | PDGFRA (0.64) | METPDGFRAKDRKITAXL | |
| SCHEMBL4403254 | 0.85 | MET (0.70) | METPDGFRAKDRKITAXL | |
| SCHEMBL29693524 | 0.85 | MET (0.70) | METPDGFRAKDRKITAXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1411046-A1 | QUINOLINE DERIVATIVE AND QUINAZOLINE DERIVATIVE INHIBITING SELF−PHOSPHORYLATION OF HEPATOCYTUS PROLIFERATOR RECEPTOR, AND MEDICINAL COMPOSITION CONTAINING THE SAME | KIRIN BEER KABUSHIKI KAISHA (JP) | 2004-04-21 | — | — | EP | claimed |