Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NT5E | P21589 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.46 |
| ▸ | PDE2A | O00408 | 1/20 | 0.46 |
| ▸ | PDE5A | O76074 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14127498 | 0.95 | GPR35 (0.51) | GPR35ALDH1A1MAPK1HIF1ATSHR | |
| Formic Acid SCHEMBL28057340 | 0.93 | GPR35 (0.50) | GPR35ALDH1A1MAPK1HIF1ATSHR | |
| SCHEMBL63183 | 0.85 | KMT2A (0.59) | GPR35ALDH1A1MAPK1HIF1ATSHR | |
| SCHEMBL1363964 | 0.85 | KMT2A (0.59) | GPR35ALDH1A1MAPK1HIF1ATSHR | |
| Water SCHEMBL7210787 | 0.84 | KMT2A (0.57) | GPR35ALDH1A1MAPK1HIF1ATSHR | |
| SCHEMBL3660349 | 0.84 | KMT2A (0.61) | GPR35ALDH1A1MAPK1HIF1ATSHR | |
| Water SCHEMBL20573516 | 0.84 | KMT2A (0.57) | GPR35ALDH1A1MAPK1HIF1ATSHR | |
| Hydrochloric Acid SCHEMBL4449301 | 0.84 | KMT2A (0.57) | GPR35ALDH1A1MAPK1HIF1ATSHR | |
| SCHEMBL3148713 | 0.84 | KMT2A (0.57) | GPR35ALDH1A1MAPK1HIF1ATSHR | |
| Water SCHEMBL29684003 | 0.84 | KMT2A (0.57) | GPR35ALDH1A1MAPK1HIF1ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10034387-B2 | Method for recycling of obsolete printed circuit boards | ENTEGRIS, INC. (US) | 2018-07-24 | — | — | US | claimed |
| US-9731368-B2 | Apparatus and method for stripping solder metals during the recycling of waste electrical and electronic equipment | ENTEGRIS, INC. (US) | 2017-08-15 | — | — | US | claimed |
| US-9649712-B2 | Apparatus and method for stripping solder metals during the recycling of waste electrical and electronic equipment | ENTEGRIS, INC. (US) | 2017-05-16 | — | — | US | claimed |
| US-20170079146-A1 | METHOD FOR RECYCLING OF OBSOLETE PRINTED CIRCUIT BOARDS | ADVANCED TECH MATERIALS (US) | 2017-03-16 | — | — | US | claimed |
| EP-2790845-B1 | APPARATUS AND METHOD FOR STRIPPING SOLDER METALS DURING THE RECYCLING OF WASTE ELECTRICAL AND ELECTRONIC EQUIPMENT | ENTEGRIS INC (US) | 2017-02-08 | — | — | EP | claimed |
| CN-103402659-B | Apparatus and method for stripping solder metal during recycling of discarded electrical and electronic equipment | MYKROLIS CORP. (US) | 2016-11-30 | — | — | CN | claimed |
| CN-103717570-B | The preparation of sitagliptin intermediate | LEK PHARMACEUTICALS D.D. (SI) | 2016-05-18 | — | — | CN | claimed |
| US-20160122846-A1 | SUSTAINABLE PROCESS FOR RECLAIMING PRECIOUS METALS AND BASE METALS FROM E-WASTE | ENTEGRIS, INC. | 2016-05-05 | — | — | US | claimed |
| US-20160095230-A1 | METHOD FOR RECYCLING OF OBSOLETE PRINTED CIRCUIT BOARDS | ENTEGRIS, INC. | 2016-03-31 | — | — | US | claimed |
| CN-103608328-B | The preparation of sitagliptin intermediate | LEK PHARMACEUTICALS D.D. (SI) | 2016-02-10 | — | — | CN | claimed |
| US-9221114-B2 | Apparatus and method for stripping solder metals during the recycling of waste electrical and electronic equipment | ADVANCED TECHNOLOGY MATERIALS, INC. (US) | 2015-12-29 | — | — | US | claimed |
| US-9215813-B2 | Method for recycling of obsolete printed circuit boards | ADVANCED TECHNOLOGY MATERIALS, INC. (US) | 2015-12-15 | — | — | US | claimed |
| EP-2714646-B1 | PREPARATION OF SITAGLIPTIN INTERMEDIATES | LEK PHARMACEUTICALS (SI) | 2015-11-04 | — | — | EP | claimed |
| US-9174930-B2 | Preparation of sitagliptin intermediates | LEK PHARMACEUTICALS D.D. (SI) | 2015-11-03 | — | — | US | claimed |
| US-20140213810-A1 | PREPARATION OF SITAGLIPTIN INTERMEDIATES | LEK PHARMACEUTICALS D.D. (SI) | 2014-07-31 | — | — | US | claimed |
| CN-103717570-A | Preparation of sitagliptin intermediates | LEK PHARMACEUTICALS | 2014-04-09 | — | — | CN | claimed |
| CN-103608328-A | Preparation of sitagliptin intermediates | LEK PHARMACEUTICALS | 2014-02-26 | — | — | CN | claimed |
| EP-2694466-A2 | PREPARATION OF SITAGLIPTIN INTERMEDIATES | LEK Pharmaceuticals d.d. (SI) | 2014-02-12 | — | — | EP | claimed |
| WO-2012136383-A2 | PREPARATION OF SITAGLIPTIN INTERMEDIATES | LEK PHARMACEUTICALS D.D. (SI) | 2012-10-11 | — | — | WO | claimed |
| EP-2508506-A1 | Preparation of sitagliptin intermediates | LEK Pharmaceuticals d.d. (SI) | 2012-10-10 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140213810-A1 | PREPARATION OF SITAGLIPTIN INTERMEDIATES | DPP4, DPP3, DPP9 | GPR35 2643/4885ALDH1A1 1546/4885MAPK1 3136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.