Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16140641 | 0.84 | ALDH1A1 (0.45) | ALDH1A1TSHRMGAMGAASI | |
| SCHEMBL8804004 | 0.84 | ALDH1A1 (0.45) | ALDH1A1TSHRMGAMGAASI | |
| SCHEMBL7636706 | 0.82 | ALDH1A1 (0.55) | ALDH1A1TSHRMGAMGAASI | |
| SCHEMBL13478059 | 0.79 | ALDH1A1 (0.43) | ALDH1A1TSHRMGAMGAASI | |
| SCHEMBL351192 | 0.76 | MGAM (0.52) | ALDH1A1TSHRMGAMGAASI | |
| SCHEMBL1849 | 0.75 | — | — | |
| SCHEMBL4390490 | 0.75 | ALDH1A1 (1.00) | ALDH1A1TSHRMGAMGAASI | |
| SCHEMBL10636466 | 0.75 | — | — | |
| SCHEMBL27466495 | 0.75 | ALDH1A1 (1.00) | ALDH1A1TSHRMGAMGAASI | |
| SCHEMBL7639036 | 0.75 | ALDH1A1 (0.46) | ALDH1A1TSHRTET2EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004098608-A1 | PYRAZOLO [4, 3-D]PYRIMIDINES, PROCESSES FOR THEIR PREPARATION AND METHODS OF USE | ÚSTAV EXPERIMENTALNI BOTANIKY AKADEMIE VED CESKE REPUBLIKY (CZ) | 2004-11-18 | — | — | WO | disclosed |