Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 10/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1879174 | 0.82 | PDE10A (0.56) | ERBB2PDE10AKDM4EALDH1A1KMT2A | |
| SCHEMBL1891795 | 0.82 | KDM4E (0.57) | ERBB2DHODHPDE10AKDM4EALDH1A1 | |
| SCHEMBL5442127 | 0.81 | PSMB5 (0.45) | DHODHPDE10AKDM4EALDH1A1KMT2A | |
| SCHEMBL1883204 | 0.80 | MBNL1 (0.43) | ERBB2DHODHPDE10AKDM4EALDH1A1 | |
| Bromide SCHEMBL3657824 | 0.80 | PDE10A (0.53) | ERBB2PDE10AKDM4EALDH1A1KMT2A | |
| SCHEMBL1882121 | 0.78 | KDM4E (0.51) | ERBB2KDM4EALDH1A1KMT2APOLB | |
| SCHEMBL3657827 | 0.78 | PDE10A (0.51) | ERBB2PDE10AKDM4EALDH1A1KMT2A | |
| SCHEMBL28536199 | 0.78 | PDE10A (0.69) | DHODHPDE10AKDM4EALDH1A1KMT2A | |
| SCHEMBL17942629 | 0.76 | DHODH (0.52) | DHODHPDE10AKDM4EALDH1A1KMT2A | |
| SCHEMBL5908712 | 0.75 | ALDH1A1 (0.42) | KDM4EALDH1A1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040102633-A1 | Novel compounds | GLAXOSMITHKLINE S.P.A. (IT) | 2004-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102633-A1 | Novel compounds | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CBR1, NR1H3 | ERBB2 2243/4885DHODH 533/4885PDE10A 2056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.