Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 3/20 | 0.41 |
| ▸ | THRA | P10827 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5935795 | 1.00 | LTA4H (0.49) | LTA4HTHRBTHRATSHRMAPT | |
| SCHEMBL3307520 | 0.98 | LTA4H (0.46) | LTA4HTHRBTHRATSHRMAPT | |
| SCHEMBL5935796 | 0.98 | LTA4H (0.50) | LTA4HTHRBTHRATSHRMAPT | |
| SCHEMBL3308645 | 0.96 | LTA4H (0.47) | LTA4HTHRBTHRATSHRMAPT | |
| SCHEMBL3303147 | 0.92 | TSHR (0.47) | LTA4HTHRBTHRATSHRMAPT | |
| SCHEMBL2494566 | 0.90 | TSHR (0.44) | LTA4HTHRBTHRATSHRMAPT | |
| SCHEMBL6671747 | 0.84 | LTA4H (0.49) | LTA4HTHRBTHRATSHRMAPT | |
| SCHEMBL3314123 | 0.83 | TSHR (0.38) | LTA4HTHRBTSHRMAPTHTT | |
| SCHEMBL15510624 | 0.82 | LTA4H (0.56) | LTA4HTHRBTHRAHRH3 | |
| SCHEMBL12120102 | 0.82 | LTA4H (0.60) | LTA4HTHRBTHRAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3553083-B2 | — | — | 2004-08-11 | — | — | JP | claimed |
| EP-0852494-A2 | PERIPHERALLY ACTIVE ANTI-HYPERALGESIC OPIATES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-07-15 | — | — | EP | claimed |
| WO-1997009973-A2 | PERIPHERALLY ACTIVE ANTI-HYPERALGESIC OPIATES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-03-20 | — | — | WO | claimed |