SCHEMBL669085

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6689667	0.92	CYP3A4 (0.61)	CYP3A4KDM4EPOLBALDH1A1TSHR
	SCHEMBL28299986	0.90	KDM4E (0.56)	CYP3A4KDM4EPOLBALDH1A1TSHR
	SCHEMBL28065146	0.89	KDM4E (0.54)	CYP3A4KDM4EPOLBALDH1A1SMN1; SMN2
	SCHEMBL668774	0.86	SMN1; SMN2 (0.58)	KDM4EPOLBALDH1A1TSHRSMN1; SMN2
	SCHEMBL7756816	0.84	CYP3A4 (0.72)	CYP3A4ALDH1A1TSHRHSD17B10KMT2A
	SCHEMBL3937140	0.83	LIG1 (0.55)	CYP3A4KDM4EPOLBALDH1A1TSHR
	SCHEMBL8787505	0.82	ALDH1A1 (0.60)	CYP3A4KDM4EPOLBALDH1A1TSHR
	SCHEMBL15813878	0.80	LIG1 (0.46)	CYP3A4KDM4EPOLBALDH1A1TSHR
	SCHEMBL8787290	0.80	ALDH1A1 (0.70)	CYP3A4KDM4EPOLBALDH1A1TSHR
	SCHEMBL9713516	0.80	CYP3A4 (0.61)	CYP3A4KDM4EPOLBALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.