Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 3/20 | 0.67 |
| ▸ | RAB9A | P51151 | 9/20 | 0.61 |
| ▸ | NPC1 | O15118 | 8/20 | 0.61 |
| ▸ | CBS | P35520 | 1/20 | 0.58 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MITF | O75030 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL131209 | 0.84 | CASR (0.67) | CASRRAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL6064770 | 0.82 | CASR (0.64) | CASRRAB9ANPC1SMN1; SMN2MITF | |
| SCHEMBL2236638 | 0.82 | EPHX1 (0.62) | CASRRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL4749812 | 0.82 | NPC1 (0.80) | CASRRAB9ANPC1CBSHPSE | |
| SCHEMBL7854890 | 0.81 | CASR (0.63) | CASRRAB9ANPC1CBSHPSE | |
| SCHEMBL30443967 | 0.81 | CASR (0.63) | CASRRAB9ANPC1CBSHPSE | |
| SCHEMBL6687855 | 0.81 | MEN1 (0.69) | CASRRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL6688583 | 0.81 | MARS1 (0.60) | CASRRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL30797219 | 0.81 | MEN1 (0.69) | CASRRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL6688636 | 0.81 | NAMPT (0.64) | RAB9ANPC1SMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004106292-A1 | HALOETHYL UREA COMPOUNDS AND THEIR USE TO ATTENUATE, INHIBIT OR PREVENT NON-CANCEROUS PATHOGENIC CELLULAR PROLIFERATION AND DISEASES ASSOCIATED THEREWITH | IMOTEP INC. (CA) | 2004-12-09 | — | — | WO | disclosed |
| WO-2004106291-A1 | HALOETHYL UREA COMPOUNDS AND THE USE THEREOF TO ATTENUATE, INHIBIT OR PREVENT CANCER CELL MIGRATION | IMOTEP INC. (CA) | 2004-12-09 | — | — | WO | disclosed |