Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8978501 | 0.79 | GPR35 (0.44) | CYP1A2GPR35MEN1KMT2AAKR1C4 | |
| SCHEMBL4367459 | 0.77 | KMT2A (0.55) | CYP1A2GPR35ALDH1A1HPGDMEN1 | |
| SCHEMBL5786219 | 0.74 | TDP1 (0.38) | CYP1A2GPR35ALDH1A1HPGDMEN1 | |
| SCHEMBL3977197 | 0.71 | AKR1C3 (0.45) | GPR35ALDH1A1HPGDAKR1C4AKR1C3 | |
| SCHEMBL3972401 | 0.64 | TTR (0.52) | TTRGPR35ALDH1A1HPGDMEN1 | |
| SCHEMBL1244129 | 0.63 | DAO (0.51) | CYP1A2GPR35ALDH1A1HPGDMEN1 | |
| SCHEMBL1901529 | 0.62 | — | — | |
| SCHEMBL3744691 | 0.62 | CYP1A2 (0.33) | CYP1A2TTRALDH1A1HPGDAKR1C4 | |
| SCHEMBL1254887 | 0.62 | — | — | |
| SCHEMBL274316 | 0.62 | CHRNA4 (0.49) | CYP1A2TTRGPR35HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040167204-A1 | Pharmacological agents and methods of treatment that inactivate pathogenic prokaryotic and eukaryotic cells and viruses by attacking highly conserved domains in structural metalloprotien and metalloenzyme targets | FERNANDEZ-POL JOSE A (US) | 2004-08-26 | — | — | US | claimed |
| US-20030225155-A1 | Pharmacological agents and methods of treatment that inactivate pathogenic prokaryotic and eukaryotic cells and viruses by attacking highly conserved domains in structural metalloprotein and metalloenzyme targets | POL'S LABORATORIOS BIOTECHNOLOGY, S.A. (AR) | 2003-12-04 | — | — | US | claimed |
| US-10188910-B2 | Golf ball | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2019-01-29 | — | — | US | disclosed |
| US-20180126226-A1 | GOLF BALL | DUNLOP SPORTS CO. LTD. (JP) | 2018-05-10 | — | — | US | disclosed |
| US-20180056137-A1 | GOLF BALL | DUNLOP SPORTS CO. LTD. (JP) | 2018-03-01 | — | — | US | disclosed |
| US-9533195-B2 | Golf ball | DUNLOP SPORTS CO. LTD. (JP) | 2017-01-03 | — | — | US | disclosed |
| US-20160144241-A1 | GOLF BALL | DUNLOP SPORTS CO. LTD. (JP) | 2016-05-26 | — | — | US | disclosed |
| US-9283439-B2 | Golf ball | DUNLOP SPORTS CO., LTD. (JP) | 2016-03-15 | — | — | US | disclosed |
| US-20140206476-A1 | GOLF BALL | DUNLOP SPORTS CO. LTD. (JP) | 2014-07-24 | — | — | US | disclosed |
| US-6803379-B2 | TREATMENT OF VIRAL, BACTERIAL, PARASITIC, PROLIFERATIVE DISEASES, NEURODEGENERATIVE DISEASES, INFLAMMATORY DISEASES, HEAVY METAL POISONING AND IMMUNOGICAL DISEASES WITH THIOPHENE-2-CARBOXYLIC ACID, 2-FUROIC ACID OR DERIVATIVES | POL'S LABORATORIOS BIOTECHNOLOGY, S.A. (AR) | 2004-10-12 | — | — | US | disclosed |
| US-20040167204-A1 | Pharmacological agents and methods of treatment that inactivate pathogenic prokaryotic and eukaryotic cells and viruses by attacking highly conserved domains in structural metalloprotien and metalloenzyme targets | FERNANDEZ-POL JOSE A (US) | 2004-08-26 | — | — | US | disclosed |
| US-20030225155-A1 | Pharmacological agents and methods of treatment that inactivate pathogenic prokaryotic and eukaryotic cells and viruses by attacking highly conserved domains in structural metalloprotein and metalloenzyme targets | POL'S LABORATORIOS BIOTECHNOLOGY, S.A. (AR) | 2003-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040167204-A1 | Pharmacological agents and methods of treatment that inactivate pathogenic prokaryotic and eukaryotic cells and viruses by attacking highly conserved domains in structural metalloprotien and metalloenzyme targets | ZFX, ZFR, SLC30A6 | CYP1A2 1303/4885TTR 33/4885GPR35 3566/4885 |
| US-20030225155-A1 | Pharmacological agents and methods of treatment that inactivate pathogenic prokaryotic and eukaryotic cells and viruses by attacking highly conserved domains in structural metalloprotein and metalloenzyme targets | ZFX, ZFR, SLC30A6 | CYP1A2 1279/4885TTR 59/4885GPR35 3614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.