Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 3/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 5/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6691050 | 1.00 | KMT2A (0.43) | KMT2AMEN1GAAMMP1ITGA4 | |
| SCHEMBL6687864 | 0.91 | MAOB (0.45) | KMT2AMEN1GAAITGA4ITGB1 | |
| SCHEMBL6687860 | 0.91 | MAOB (0.45) | KMT2AMEN1GAAITGA4ITGB1 | |
| SCHEMBL6690944 | 0.85 | MAOB (0.48) | ITGA4ITGB1LMNACD274MAOA | |
| SCHEMBL6693470 | 0.83 | LMNA (0.44) | KMT2AMEN1GAASMN1; SMN2LMNA | |
| SCHEMBL6685476 | 0.80 | MAOB (0.47) | KMT2AMEN1GAASMN1; SMN2LMNA | |
| SCHEMBL6685482 | 0.80 | MAOB (0.47) | KMT2AMEN1GAASMN1; SMN2LMNA | |
| SCHEMBL6687664 | 0.79 | MAOB (0.59) | LMNACD274MAOAMAOB | |
| SCHEMBL6687667 | 0.79 | MAOB (0.59) | LMNACD274MAOAMAOB | |
| SCHEMBL6690108 | 0.77 | SMN1; SMN2 (0.56) | KMT2AMEN1GAASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087125-A1 | AMINO ACID DERIVATIVES AS INHIBITORS OF MAMMALIAN SODIUM CHANNELS | IONIX PHARMACEUTICALS LIMITED (GB) | 2004-10-14 | — | — | WO | disclosed |