SCHEMBL6690953

SCHEMBL6690953

CCOc1cccc2nc(SSc3nc4cccc(OCC)c4s3)sc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 4/20 0.52
HSP90AB1 P08238 4/20 0.52
ALDH1A1 P00352 5/20 0.43
KDM4E B2RXH2 3/20 0.43
HSD17B10 Q99714 2/20 0.43
MAPK1 P28482 2/20 0.43
PDK1 Q15118 3/20 0.42
FBP1 P09467 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
ADRA2A P08913 1/20 0.42
ADORA3 P0DMS8 1/20 0.42
DRD2 P14416 1/20 0.42
HPGD P15428 1/20 0.42
ALOX15 P16050 1/20 0.42
ADRA2B P18089 1/20 0.42
ADRA2C P18825 1/20 0.42
DRD1 P21728 1/20 0.42
MC5R P33032 1/20 0.42
OPRM1 P35372 1/20 0.42
DRD3 P35462 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7057168 0.91 HSP90AA1 (0.54) HSP90AA1HSP90AB1ALDH1A1KDM4EHSD17B10
SCHEMBL8652292 0.88 HSP90AA1 (0.50) HSP90AA1HSP90AB1ALDH1A1KDM4EHSD17B10
SCHEMBL6694187 0.87 HSP90AA1 (0.49) HSP90AA1HSP90AB1ALDH1A1HSD17B10PDK1
SCHEMBL6696720 0.84 HSP90AA1 (0.45) HSP90AA1HSP90AB1ALDH1A1KDM4EHSD17B10
SCHEMBL6691814 0.83 ALDH1A1 (0.47) HSP90AA1HSP90AB1ALDH1A1KDM4EHSD17B10
SCHEMBL6689394 0.82 HSP90AA1 (0.44) HSP90AA1HSP90AB1ALDH1A1KDM4EHSD17B10
SCHEMBL5038688 0.79 ALDH1A1 (0.48) HSP90AA1HSP90AB1ALDH1A1KDM4EHSD17B10
SCHEMBL30967515 0.79 ALDH1A1 (0.48) HSP90AA1HSP90AB1ALDH1A1KDM4EHSD17B10
SCHEMBL9306062 0.79 ALDH1A1 (0.59) HSP90AA1HSP90AB1ALDH1A1KDM4EHSD17B10
SCHEMBL6694242 0.77 ALDH1A1 (0.56) HSP90AA1HSP90AB1ALDH1A1KDM4EMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0869016-B1 Pneumatic radial tires BRIDGESTONE CORP (JP) 2004-03-03 EP disclosed
EP-0890605-B1 Pneumatic tire BRIDGESTONE CORP (JP) 2003-04-23 EP disclosed
EP-1277795-A2 Pneumatic tire BRIDGESTONE CORPORATION (JP) 2003-01-22 EP disclosed
US-20020010283-A1 RUBBER COMPOSITION BRIDGESTONE CORPORATION (JP) 2002-01-24 US disclosed
US-6336486-B1 Pneumatic radical tire having cap base tread BRIDGESTONE CORPORATION (JP) 2002-01-08 US disclosed
US-6186204-B1 EXCELLENT STABILITY AND CONTROLLABILITY ON WET ROADS OR A COMBINATION OF STABILITY AND CONTROLLABILITY ON WET ROADS AND EXCELLENT COMFORT OF RIDE EVEN WHEN A VEHICLE IS VIBRATING THROUGHOUT THE LIFE OF THE PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2001-02-13 US disclosed
EP-0890605-A2 Pneumatic tire BRIDGESTONE CORPORATION (JP) 1999-01-13 EP disclosed
EP-0869016-A2 Pneumatic radial tires Bridgestone Corporation (JP) 1998-10-07 EP disclosed
EP-0854168-A1 Rubber composition Bridgestone Corporation (JP) 1998-07-22 EP disclosed