Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GUSB | P08236 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2749006 | 0.83 | ALDH1A1 (0.58) | ALDH1A1KMT2AKDM4EMAPTMEN1 | |
| SCHEMBL5038688 | 0.81 | ALDH1A1 (0.48) | ALDH1A1KMT2AKDM4EMAPK1HSD17B10 | |
| SCHEMBL30967515 | 0.81 | ALDH1A1 (0.48) | ALDH1A1KMT2AKDM4EMAPK1HSD17B10 | |
| SCHEMBL7057168 | 0.79 | HSP90AA1 (0.54) | ALDH1A1KMT2AKDM4EMAPK1HSD17B10 | |
| SCHEMBL6690953 | 0.79 | HSP90AA1 (0.52) | ALDH1A1KMT2AKDM4EMAPK1HSD17B10 | |
| SCHEMBL31726106 | 0.78 | KMT2A (0.49) | ALDH1A1KMT2AKDM4EMAPK1HSD17B10 | |
| SCHEMBL8652292 | 0.77 | HSP90AA1 (0.50) | ALDH1A1KMT2AKDM4EMAPK1HSD17B10 | |
| SCHEMBL30189857 | 0.75 | ALDH1A1 (0.39) | ALDH1A1KMT2AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL19783259 | 0.75 | ALDH1A1 (0.39) | ALDH1A1KMT2AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL27848467 | 0.75 | KMT2A (0.40) | ALDH1A1KMT2AKDM4EMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-5152929-A | Corrosion inhibitors for water systems | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0129506-B1 | HETEROCYCLICALLY SUBSTITUTED THIO(CYCLO)ALKANE POLYCARBOXYLIC ACIDS | CIBA-GEIGY AG (CH) | 1991-03-06 | — | — | EP | disclosed |
| EP-0129506-A2 | Heterocyclically substituted thio(cyclo)alkane polycarboxylic acids | CIBA-GEIGY AG (CH) | 1984-12-27 | — | — | EP | disclosed |
| US-4264769-A | BY REACTING A DIHYDROXYBENZENE WITH A HETEROCYCLIC OR PHENYL HALIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1981-04-28 | — | — | US | disclosed |
| EP-0003562-A1 | Process for the preparation of hydroxyphenyl ethers | BAYER AG (DE) | 1979-08-22 | — | — | EP | disclosed |