Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 3/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CASR | P41180 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23457301 | 0.84 | MAPT (0.70) | MAPTKMT2AMEN1EPHX1HTT | |
| SCHEMBL6689221 | 0.84 | MAPT (0.50) | MAPTSMN1; SMN2KMT2AMEN1EPHX1 | |
| SCHEMBL30797219 | 0.83 | MEN1 (0.69) | MAPTSMN1; SMN2KMT2AMEN1EPHX1 | |
| SCHEMBL6688583 | 0.83 | MARS1 (0.60) | MAPTSMN1; SMN2KMT2AMEN1EPHX1 | |
| SCHEMBL6687855 | 0.83 | MEN1 (0.69) | MAPTSMN1; SMN2KMT2AMEN1EPHX1 | |
| SCHEMBL5054174 | 0.81 | MARS1 (0.61) | MAPTSMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL6690632 | 0.81 | EGFR (0.64) | MAPTSMN1; SMN2KMT2AMEN1EPHX1 | |
| SCHEMBL3781565 | 0.81 | ALDH1A1 (0.67) | MAPTSMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL6690864 | 0.81 | MAPT (0.75) | MAPTSMN1; SMN2KMT2AEPHX1LMNA | |
| SCHEMBL29466759 | 0.81 | GRIK1 (0.60) | MAPTSMN1; SMN2KMT2AMEN1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004106292-A1 | HALOETHYL UREA COMPOUNDS AND THEIR USE TO ATTENUATE, INHIBIT OR PREVENT NON-CANCEROUS PATHOGENIC CELLULAR PROLIFERATION AND DISEASES ASSOCIATED THEREWITH | IMOTEP INC. (CA) | 2004-12-09 | — | — | WO | disclosed |
| WO-2004106291-A1 | HALOETHYL UREA COMPOUNDS AND THE USE THEREOF TO ATTENUATE, INHIBIT OR PREVENT CANCER CELL MIGRATION | IMOTEP INC. (CA) | 2004-12-09 | — | — | WO | disclosed |