Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10626206 | 0.94 | LMNA (0.57) | TSHRKMT2AHSD17B10ALDH1A1TP53 | |
| SCHEMBL6690420 | 0.88 | ATP4A (0.44) | TSHRKMT2AHSD17B10ALDH1A1TP53 | |
| SCHEMBL346596 | 0.88 | KMT2A (0.68) | TSHRKMT2AHSD17B10ALDH1A1TP53 | |
| SCHEMBL28028162 | 0.85 | ATP4A (0.42) | TSHRALDH1A1KDM4EATP4AATP4B | |
| SCHEMBL10425847 | 0.85 | CA1 (0.61) | TSHRKMT2AHSD17B10ALDH1A1TP53 | |
| SCHEMBL10383598 | 0.84 | NR5A1 (0.43) | TSHRTP53ATP4AATP4B | |
| SCHEMBL14093807 | 0.84 | NR5A1 (0.43) | TSHRTP53ATP4AATP4B | |
| Isobutane SCHEMBL8361660 | 0.84 | KMT2A (0.62) | TSHRKMT2AHSD17B10ALDH1A1TP53 | |
| SCHEMBL12111155 | 0.83 | TDP1 (0.57) | TSHRKMT2AHSD17B10ALDH1A1TP53 | |
| SCHEMBL16155847 | 0.83 | KMT2A (0.54) | TSHRKMT2AHSD17B10ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4724072-A | 2-MERCAPTOBENZOTHIAZOLE DERIVATIVES | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 1988-02-09 | — | — | US | claimed |
| EP-0869016-B1 | Pneumatic radial tires | BRIDGESTONE CORP (JP) | 2004-03-03 | — | — | EP | disclosed |
| EP-0945482-B1 | Rubber composition for tire tread and pneumatic tire using same | BRIDGESTONE CORP (JP) | 2004-01-28 | — | — | EP | disclosed |
| EP-0890605-B1 | Pneumatic tire | BRIDGESTONE CORP (JP) | 2003-04-23 | — | — | EP | disclosed |
| EP-1277795-A2 | Pneumatic tire | BRIDGESTONE CORPORATION (JP) | 2003-01-22 | — | — | EP | disclosed |
| US-20020010283-A1 | RUBBER COMPOSITION | BRIDGESTONE CORPORATION (JP) | 2002-01-24 | — | — | US | disclosed |
| US-6336486-B1 | Pneumatic radical tire having cap base tread | BRIDGESTONE CORPORATION (JP) | 2002-01-08 | — | — | US | disclosed |
| US-6242522-B1 | A DIENE BASED SYNTHETIC RUBBER OR NATURAL RUBBER BLEND CONTAINING BUTADIENE-STYRENE RUBBER, ALUMINUM HYDROXIDE POWDER, SILICA POWDER, CARBON BLACK; LOW FUEL CONSUMPTION AND WEAR RESISTANCE; IMPROVED GRIPPING IN WET AND COLD SITUATIONS | BRIDGESTONE CORPORATION (JP) | 2001-06-05 | — | — | US | disclosed |
| US-6186204-B1 | EXCELLENT STABILITY AND CONTROLLABILITY ON WET ROADS OR A COMBINATION OF STABILITY AND CONTROLLABILITY ON WET ROADS AND EXCELLENT COMFORT OF RIDE EVEN WHEN A VEHICLE IS VIBRATING THROUGHOUT THE LIFE OF THE PNEUMATIC TIRE | BRIDGESTONE CORPORATION (JP) | 2001-02-13 | — | — | US | disclosed |
| EP-0948029-A2 | High pressure discharge lamp | NGK INSULATORS, LTD. (JP) | 1999-10-06 | — | — | EP | disclosed |
| EP-0890605-A2 | Pneumatic tire | BRIDGESTONE CORPORATION (JP) | 1999-01-13 | — | — | EP | disclosed |
| EP-0869016-A2 | Pneumatic radial tires | Bridgestone Corporation (JP) | 1998-10-07 | — | — | EP | disclosed |
| EP-0854168-A1 | Rubber composition | Bridgestone Corporation (JP) | 1998-07-22 | — | — | EP | disclosed |
| US-4946585-A | USING MERCAPTOBENZOTHIAZOLE | AMERICAN CYANAMID COMPANY (US) | 1990-08-07 | — | — | US | disclosed |
| US-4724072-A | 2-MERCAPTOBENZOTHIAZOLE DERIVATIVES | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 1988-02-09 | — | — | US | disclosed |