Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CLK1 | P49759 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | FASN | P49327 | 1/20 | 0.42 |
| ▸ | P4HB | P07237 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12473724 | 0.87 | CES2 (0.59) | CA12CA1CA2CA6CA9 | |
| SCHEMBL6688051 | 0.87 | CES2 (0.59) | CA12CA1CA2CA6CA9 | |
| SCHEMBL12473723 | 0.87 | CES2 (0.59) | CA12CA1CA2CA6CA9 | |
| SCHEMBL8937260 | 0.77 | CES2 (0.55) | CES2KDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL8937266 | 0.77 | CES2 (0.55) | CES2KDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL8937263 | 0.77 | CES2 (0.55) | CES2KDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL63954 | 0.77 | CES1 (0.50) | CA12CA1CA2CA6CA9 | |
| Paraben SCHEMBL9489073 | 0.76 | CA12 (0.83) | CA12CA1CA2CA6CA9 | |
| SCHEMBL23259265 | 0.75 | MAPT (0.49) | CA12CA1CA2CA9PARP1 | |
| SCHEMBL6339843 | 0.75 | CA12 (0.57) | CA12CA1CA2CA6CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084854-A1 | COSMETIC USE OF CINNAMIC ACID DERIVATIVES AS LIGHTENING AGENTS | L'OREAL (FR) | 2004-10-07 | — | — | WO | claimed |
| WO-2004084854-A1 | COSMETIC USE OF CINNAMIC ACID DERIVATIVES AS LIGHTENING AGENTS | L'OREAL (FR) | 2004-10-07 | — | — | WO | disclosed |