Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31439507 | 0.84 | ALDH1A1 (0.73) | ALDH1A1SMN1; SMN2KMT2AMEN1BLM | |
| SCHEMBL4395595 | 0.84 | ALDH1A1 (0.73) | ALDH1A1SMN1; SMN2KMT2AMEN1BLM | |
| SCHEMBL6695143 | 0.83 | KDM4E (0.48) | ALDH1A1SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL6691256 | 0.83 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL6692065 | 0.83 | KDM4E (0.48) | ALDH1A1SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL6692060 | 0.83 | KDM4E (0.48) | ALDH1A1SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL7235813 | 0.82 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2KMT2AMEN1BLM | |
| SCHEMBL9474574 | 0.82 | POLB (0.59) | ALDH1A1SMN1; SMN2KMT2AMEN1BLM | |
| SCHEMBL6691260 | 0.79 | KDM4E (0.56) | ALDH1A1SMN1; SMN2LMNAKDM4EHPGD | |
| SCHEMBL2966492 | 0.76 | SOAT1 (0.59) | ALDH1A1SMN1; SMN2KMT2ALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0950669-B1 | Method of catalytic crosslinking of polymers and two-pack composition used therein | ROHM & HAAS (US) | 2004-09-08 | — | — | EP | disclosed |
| US-6306991-B1 | TWO PART COATING COMPOSITION WITH TWO CONTAINERS, OXIDATIVE POLYMERS WITH CROSSLINKABLE FUNCTIONAL GROUPS | ROHM AND HAAS COMPANY | 2001-10-23 | — | — | US | disclosed |
| US-6149977-A | CONTACTING THE OXIDATIVE POLYMER WITH A CATALYTIC AMOUNT OF AN OXIDIZING ENZYME, SUCH AS HORSERADISH PEROXIDASE. | ROHM AND HAAS COMPANY (US) | 2000-11-21 | — | — | US | disclosed |
| EP-0950669-A2 | Method of catalytic crosslinking of polymers and two-pack composition used therein | ROHM AND HAAS COMPANY (US) | 1999-10-20 | — | — | EP | disclosed |