Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2628001 | 0.84 | KMT2A (0.65) | KDM4ELMNASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL6692060 | 0.83 | KDM4E (0.48) | KDM4ELMNASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL6691248 | 0.83 | ALDH1A1 (0.58) | KDM4ELMNASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL6692069 | 0.83 | KMT2A (0.42) | KDM4ELMNASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL30720450 | 0.83 | KDM4E (0.48) | KDM4ELMNASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL6695143 | 0.83 | KDM4E (0.48) | KDM4ELMNASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL22833193 | 0.83 | KMT2A (0.58) | KDM4EALDH1A1KMT2AHPGDPOLB | |
| SCHEMBL22406054 | 0.82 | POLB (0.59) | KDM4ELMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL8478828 | 0.82 | TSHR (0.49) | KDM4ELMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL6692441 | 0.79 | KDM4E (0.56) | KDM4ELMNASMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0950669-B1 | Method of catalytic crosslinking of polymers and two-pack composition used therein | ROHM & HAAS (US) | 2004-09-08 | — | — | EP | disclosed |
| US-6306991-B1 | TWO PART COATING COMPOSITION WITH TWO CONTAINERS, OXIDATIVE POLYMERS WITH CROSSLINKABLE FUNCTIONAL GROUPS | ROHM AND HAAS COMPANY | 2001-10-23 | — | — | US | disclosed |
| US-6149977-A | CONTACTING THE OXIDATIVE POLYMER WITH A CATALYTIC AMOUNT OF AN OXIDIZING ENZYME, SUCH AS HORSERADISH PEROXIDASE. | ROHM AND HAAS COMPANY (US) | 2000-11-21 | — | — | US | disclosed |
| EP-0950669-A2 | Method of catalytic crosslinking of polymers and two-pack composition used therein | ROHM AND HAAS COMPANY (US) | 1999-10-20 | — | — | EP | disclosed |