SCHEMBL6691280

SCHEMBL6691280

CCCCCCCCCCCCCCCCCC(O)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.43
POLB P06746 2/20 0.42
LMNA P02545 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
ALDH1A1 P00352 2/20 0.42
ASAH2 Q9NR71 1/20 0.41
GRM8 O00222 3/20 0.40
GRM4 Q14833 3/20 0.40
MEN1 O00255 1/20 0.40
HPGD P15428 1/20 0.40
KMT2A Q03164 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
ADRB2 P07550 4/20 0.39
MGLL Q99685 1/20 0.39
HTT P42858 1/20 0.39
CYP19A1 P11511 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28047548 0.84 POLB (0.39) POLBLMNACYP3A4CYP2D6CYP2C9
SCHEMBL19339253 0.78 L3MBTL1 (0.60) LMNACYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL9392854 0.77 ALDH1A1 (0.62) LMNANPSR1ALDH1A1ASAH2MEN1
Pentane SCHEMBL21693644 0.76 CYP19A1 (0.56) POLBLMNACYP3A4ALDH1A1MEN1
SCHEMBL7589193 0.75 CYP3A4 (0.47) LMNACYP3A4ALDH1A1GRM8GRM4
SCHEMBL28013194 0.75 POLB (0.40) POLBLMNAALDH1A1GRM8GRM4
SCHEMBL9026367 0.74 ALDH1A1 (0.44) CA2POLBCYP2C9ALDH1A1MEN1
SCHEMBL9157996 0.73 L3MBTL1 (0.62) LMNACYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL9158002 0.73 L3MBTL1 (0.62) LMNACYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL19829355 0.73 KCNH2 (0.55) POLBCYP3A4HTTCYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004067623-A2 POLYMIDE RESIN FOR NON-RUBBING VERTICAL ALIGNMENT MATERIALS AND PREPARATION METHOD THEREOF KIM YONG-BAE (KR) 2004-08-12 WO disclosed