Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | BLM | P54132 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 6/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 6/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 6/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | DRD1 | P21728 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25272308 | 0.82 | ABCB1 (0.41) | HIF1AKDM4EALDH1A1SMN1; SMN2ADRB1 | |
| SCHEMBL6323564 | 0.78 | CYP2D6 (0.54) | HIF1AKDM4EBLMTDP1HTR1A | |
| SCHEMBL1205146 | 0.78 | CYP2D6 (0.54) | HIF1AKDM4EBLMTDP1HTR1A | |
| SCHEMBL4055320 | 0.78 | CYP2D6 (0.54) | HIF1AKDM4EBLMTDP1HTR1A | |
| SCHEMBL12495184 | 0.77 | TAAR1 (0.41) | HIF1AKDM4EBLMTDP1TAAR1 | |
| SCHEMBL6839728 | 0.77 | P2RX7 (0.35) | CYP1A2P2RX7 | |
| Hydrochloric Acid SCHEMBL6282414 | 0.76 | CYP2D6 (0.52) | HIF1AKDM4EBLMTDP1HTR1A | |
| Hydrochloric Acid SCHEMBL6668150 | 0.76 | CYP2D6 (0.52) | HIF1AKDM4EBLMTDP1HTR1A | |
| SCHEMBL25270869 | 0.76 | KDM4E (0.46) | KDM4EHTR1AALDH1A1ADRB2LMNA | |
| SCHEMBL28595047 | 0.74 | GOT1 (0.34) | CYP1A2P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110787-A1 | Heteroaryl-ethanolamine derivatives as antiviral agents | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | disclosed |
| WO-2004022567-A1 | HETEROARYL-ETHANOLAMINE DERIVATIVES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110787-A1 | Heteroaryl-ethanolamine derivatives as antiviral agents | RPL35, ZC3HAV1, RPL5 | HIF1A 2960/4885KDM4E 775/4885BLM 2510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.