SCHEMBL6691556

SCHEMBL6691556

CCN1c2ccc(OC)cc2SC1S[N]

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SNCA P37840 5/20 0.37
▸ CACNA1S Q13698 2/20 0.36
▸ LMNA P02545 2/20 0.36
▸ MAPT P10636 4/20 0.34
▸ HSD17B10 Q99714 3/20 0.34
▸ ALDH1A1 P00352 3/20 0.34
▸ NPSR1 Q6W5P4 3/20 0.34
▸ PIM1 P11309 2/20 0.34
▸ CSNK1D P48730 2/20 0.34
▸ CSNK1E P49674 2/20 0.34
▸ CLK1 P49759 2/20 0.34
▸ CLK3 P49761 2/20 0.34
▸ CSNK1G2 P78368 2/20 0.34
▸ DYRK1A Q13627 2/20 0.34
▸ MAP3K19 Q56UN5 2/20 0.34
▸ PIM3 Q86V86 2/20 0.34
▸ DYRK1B Q9Y463 2/20 0.34
▸ CSNK1G3 Q9Y6M4 2/20 0.34
▸ HPGD P15428 2/20 0.34
▸ HTT P42858 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6694898 0.89 MAPT (0.39) SNCALMNAMAPTHSD17B10ALDH1A1
SCHEMBL6691825 0.86 SNCA (0.40) SNCACACNA1SLMNAMAPTHSD17B10
SCHEMBL29039151 0.80 LMNA (0.42) SNCACACNA1SLMNAMAPTHSD17B10
SCHEMBL6693802 0.79 SNCA (0.38) SNCACACNA1SLMNAMAPTALDH1A1
Iodide SCHEMBL11207200 0.78 LMNA (0.41) SNCACACNA1SLMNAMAPTHSD17B10
SCHEMBL6690962 0.75 MEN1 (0.41) SNCALMNAMAPTHSD17B10ALDH1A1
SCHEMBL6698691 0.75 HTR2A (0.33) MAPTALDH1A1GAAMEN1KMT2A
SCHEMBL6693731 0.74 KMT2A (0.37) LMNAMAPTHSD17B10ALDH1A1HPGD
SCHEMBL6693170 0.74 MPI (0.38) SNCALMNAALDH1A1NPSR1CYP3A4
SCHEMBL6697188 0.70 KMT2A (0.33) MAPTHSD17B10ALDH1A1APOBEC3GMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0869016-B1 Pneumatic radial tires BRIDGESTONE CORP (JP) 2004-03-03 — — EP disclosed
EP-0890605-B1 Pneumatic tire BRIDGESTONE CORP (JP) 2003-04-23 — — EP disclosed
US-20020010283-A1 RUBBER COMPOSITION BRIDGESTONE CORPORATION (JP) 2002-01-24 — — US disclosed
US-6336486-B1 Pneumatic radical tire having cap base tread BRIDGESTONE CORPORATION (JP) 2002-01-08 — — US disclosed
EP-0890605-A2 Pneumatic tire BRIDGESTONE CORPORATION (JP) 1999-01-13 — — EP disclosed
EP-0869016-A2 Pneumatic radial tires Bridgestone Corporation (JP) 1998-10-07 — — EP disclosed
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