Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 7/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6697218 | 0.90 | CYP1A2 (0.32) | SNCALMNAKDM4EALDH1A1NOTUM | |
| SCHEMBL6692273 | 0.87 | SNCA (0.40) | SNCALMNACACNA1SKDM4EALDH1A1 | |
| SCHEMBL6697188 | 0.85 | KMT2A (0.33) | KDM4EALDH1A1MEN1MAPTMAPK1 | |
| SCHEMBL6691556 | 0.79 | SNCA (0.37) | SNCALMNACACNA1SKDM4EALDH1A1 | |
| SCHEMBL6696740 | 0.76 | SNCA (0.34) | SNCALMNAKDM4EALDH1A1MEN1 | |
| SCHEMBL6693472 | 0.76 | MEN1 (0.33) | KDM4EALDH1A1MEN1MAPTMAPK1 | |
| SCHEMBL6693170 | 0.75 | MPI (0.38) | SNCALMNAKDM4EALDH1A1CYP1A2 | |
| SCHEMBL6693788 | 0.73 | MEN1 (0.35) | LMNAKDM4EALDH1A1MEN1MAPT | |
| SCHEMBL6691038 | 0.71 | TSHR (0.33) | LMNAALDH1A1MEN1GAAMAPT | |
| SCHEMBL6694898 | 0.70 | MAPT (0.39) | SNCALMNAKDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869016-B1 | Pneumatic radial tires | BRIDGESTONE CORP (JP) | 2004-03-03 | — | — | EP | disclosed |
| US-6336486-B1 | Pneumatic radical tire having cap base tread | BRIDGESTONE CORPORATION (JP) | 2002-01-08 | — | — | US | disclosed |
| EP-0869016-A2 | Pneumatic radial tires | Bridgestone Corporation (JP) | 1998-10-07 | — | — | EP | disclosed |