Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.50 |
| ▸ | CNR1 | P21554 | 7/20 | 0.50 |
| ▸ | PPARA | Q07869 | 3/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | PPARD | Q03181 | 2/20 | 0.49 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.41 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL669178 | 1.00 | CNR2 (0.50) | CNR2CNR1PPARATRPA1TRPV1 | |
| SCHEMBL10300846 | 1.00 | CNR2 (0.50) | CNR2CNR1PPARATRPA1TRPV1 | |
| SCHEMBL669179 | 1.00 | CNR2 (0.50) | CNR2CNR1PPARATRPA1TRPV1 | |
| SCHEMBL3306709 | 0.98 | CNR2 (0.53) | CNR2CNR1PPARATRPA1TRPV1 | |
| Hydrochloric Acid SCHEMBL1875601 | 0.98 | CNR2 (0.49) | CNR2CNR1PPARATRPA1TRPV1 | |
| SCHEMBL3306703 | 0.98 | CNR2 (0.53) | CNR2CNR1PPARATRPA1TRPV1 | |
| SCHEMBL17540809 | 0.98 | CNR2 (0.53) | CNR2CNR1PPARATRPA1TRPV1 | |
| SCHEMBL8345725 | 0.98 | CNR2 (0.53) | CNR2CNR1PPARATRPA1TRPV1 | |
| SCHEMBL4245971 | 0.91 | PPARA (0.60) | CNR2CNR1PPARATRPA1TRPV1 | |
| SCHEMBL8347693 | 0.91 | PPARA (0.60) | CNR2CNR1PPARATRPA1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023213310-A9 | CARBON CHAIN SUBSTANCE FOR REGULATING TRANSMEMBRANE TRANSPORT AND FLUIDITY OF CELL MEMBRANES, AND PREPARATION AND USE THEREOF | 太阳雨林(北京)生物医药有限公司 | 2025-02-20 | — | — | WO | disclosed |
| EP-2605664-A1 | MOUTH-MOISTENING GUM COMPOSITIONS AND PRODUCTS CONTAINING THE SAME | Kraft Foods Global Brands LLC (US) | 2013-06-26 | — | — | EP | disclosed |
| EP-2584911-A1 | ENHANCED RELEASE OF LIPOPHILIC INGREDIENTS FROM CHEWING GUM WITH HYDROCOLLOIDS | Kraft Foods Global Brands LLC (US) | 2013-05-01 | — | — | EP | disclosed |
| US-8217192-B2 | Production method of (2E,6Z,8E)-N-isobutyl-2,6,8-decatrienamide (spilanthol), and food or drink, fragrance or cosmetic, or pharmaceutical comprising the same | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2012-07-10 | — | — | US | disclosed |
| WO-2012024410-A1 | MOUTH-MOISTENING GUM COMPOSITIONS AND PRODUCTS CONTAINING THE SAME | KRAFT FOODS GLOBAL BRANDS LLC (US) | 2012-02-23 | — | — | WO | disclosed |
| WO-2011163152-A1 | ENHANCED RELEASE OF LIPOPHILIC INGREDIENTS FROM CHEWING GUM WITH HYDROCOLLOIDS | KRAFT FOODS GLOBAL BRANDS LLC (US) | 2011-12-29 | — | — | WO | disclosed |
| US-20110105773-A1 | PRODUCTION METHOD OF (2E,6Z,8E)-N-ISOBUTYL-2,6,8-DECATRIENAMIDE (SPILANTHOL), AND FOOD OR DRINK, FRAGRANCE OR COSMETIC, OR PHARMACEUTICAL COMPRISING THE SAME | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-05-05 | — | — | US | disclosed |
| EP-2236489-A1 | METHOD FOR PRODUCTION OF (2E,6Z,8E)-N-ISOBUTYL-2,6,8-DECATRIENAMIDE (SPILANTHOL), AND FOODS, BEVERAGES, COSMETICS AND PHARMACEUTICAL PREPARATIONS EACH COMPRISING THE COMPOUND | Takasago International Corporation (JP) | 2010-10-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105773-A1 | PRODUCTION METHOD OF (2E,6Z,8E)-N-ISOBUTYL-2,6,8-DECATRIENAMIDE (SPILANTHOL), AND FOOD OR DRINK, FRAGRANCE OR COSMETIC, OR PHARMACEUTICAL COMPRISING THE SAME | NISCH, FAAH2, ADH5 | CNR2 7/4885CNR1 43/4885PPARA 222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.