Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 7/20 | 0.50 |
| ▸ | RAB9A | P51151 | 7/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | APP | P05067 | 2/20 | 0.49 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6690955 | 0.89 | PPARA (0.56) | PDK1MAPTL3MBTL1LMNAMAPK1 | |
| SCHEMBL6693725 | 0.88 | MAPT (0.61) | MAPTL3MBTL1LMNAMAPK1CYP1A2 | |
| SCHEMBL6688601 | 0.85 | PPARA (0.50) | PDK1MAPTL3MBTL1LMNAMAPK1 | |
| SCHEMBL6692270 | 0.81 | PDK1 (0.67) | PDK1MAPTL3MBTL1LMNAMAPK1 | |
| SCHEMBL6902779 | 0.81 | PDK1 (0.81) | PDK1MAPTL3MBTL1LMNAMAPK1 | |
| SCHEMBL6693668 | 0.81 | PDK1 (1.00) | PDK1MAPTL3MBTL1LMNAMAPK1 | |
| SCHEMBL31291763 | 0.79 | PDK1 (0.79) | PDK1MAPTL3MBTL1LMNAMAPK1 | |
| SCHEMBL9389916 | 0.78 | PDK1 (0.67) | PDK1MAPTL3MBTL1LMNAMAPK1 | |
| SCHEMBL10810319 | 0.77 | PDK1 (0.62) | PDK1MAPTL3MBTL1LMNAMAPK1 | |
| SCHEMBL28589570 | 0.77 | PDK1 (0.70) | PDK1MAPTL3MBTL1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869016-B1 | Pneumatic radial tires | BRIDGESTONE CORP (JP) | 2004-03-03 | — | — | EP | disclosed |
| EP-0945482-B1 | Rubber composition for tire tread and pneumatic tire using same | BRIDGESTONE CORP (JP) | 2004-01-28 | — | — | EP | disclosed |
| EP-1277795-A2 | Pneumatic tire | BRIDGESTONE CORPORATION (JP) | 2003-01-22 | — | — | EP | disclosed |
| US-20020010283-A1 | RUBBER COMPOSITION | BRIDGESTONE CORPORATION (JP) | 2002-01-24 | — | — | US | disclosed |
| US-6336486-B1 | Pneumatic radical tire having cap base tread | BRIDGESTONE CORPORATION (JP) | 2002-01-08 | — | — | US | disclosed |
| US-6242522-B1 | A DIENE BASED SYNTHETIC RUBBER OR NATURAL RUBBER BLEND CONTAINING BUTADIENE-STYRENE RUBBER, ALUMINUM HYDROXIDE POWDER, SILICA POWDER, CARBON BLACK; LOW FUEL CONSUMPTION AND WEAR RESISTANCE; IMPROVED GRIPPING IN WET AND COLD SITUATIONS | BRIDGESTONE CORPORATION (JP) | 2001-06-05 | — | — | US | disclosed |
| US-6186204-B1 | EXCELLENT STABILITY AND CONTROLLABILITY ON WET ROADS OR A COMBINATION OF STABILITY AND CONTROLLABILITY ON WET ROADS AND EXCELLENT COMFORT OF RIDE EVEN WHEN A VEHICLE IS VIBRATING THROUGHOUT THE LIFE OF THE PNEUMATIC TIRE | BRIDGESTONE CORPORATION (JP) | 2001-02-13 | — | — | US | disclosed |
| EP-0948029-A2 | High pressure discharge lamp | NGK INSULATORS, LTD. (JP) | 1999-10-06 | — | — | EP | disclosed |
| EP-0890605-A2 | Pneumatic tire | BRIDGESTONE CORPORATION (JP) | 1999-01-13 | — | — | EP | disclosed |
| EP-0869016-A2 | Pneumatic radial tires | Bridgestone Corporation (JP) | 1998-10-07 | — | — | EP | disclosed |
| EP-0854168-A1 | Rubber composition | Bridgestone Corporation (JP) | 1998-07-22 | — | — | EP | disclosed |