Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5365885 | 0.84 | ITGB1 (1.00) | ITGB1ITGA4 | |
| SCHEMBL6107350 | 0.82 | ITGB1 (0.81) | ITGB1ITGA4 | |
| SCHEMBL5369340 | 0.81 | ITGB1 (1.00) | ITGB1ITGA4 | |
| SCHEMBL6695624 | 0.78 | ITGB1 (0.74) | ITGB1ITGA4 | |
| SCHEMBL7450089 | 0.78 | ITGB1 (0.74) | ITGB1ITGA4 | |
| SCHEMBL5361624 | 0.78 | ITGB1 (1.00) | ITGB1ITGA4 | |
| SCHEMBL5377622 | 0.77 | ITGB1 (0.73) | ITGB1ITGA4 | |
| SCHEMBL5360046 | 0.77 | ITGB1 (1.00) | ITGB1ITGA4 | |
| SCHEMBL5363884 | 0.77 | ITGB1 (1.00) | ITGB1ITGA4 | |
| SCHEMBL5370384 | 0.76 | ITGB1 (0.72) | ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677339-B2 | S-3-(4-(3,5-DICHLOROPYRID-4-YLCARBOXAMIDO)PHENYL)-2-(4,6-DIMET HOXY-1,3,5-TRIAZIN-2-YLAMINO)PROPANOIC ACID FOR EXAMPLE; INHIBIT BINDING OF ALPHA 4 INTEGRINS TO THEIR LIGANDS, FOR TREATING IMMUNE OR INFLAMMATORY DISORDERS | CELLTECH R & D LIMITED (GB) | 2004-01-13 | — | — | US | disclosed |
| US-20020028812-A1 | Phenylalanine derivatives | CELLTECH CHIROSCIENCE LIMITED (GB) | 2002-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020028812-A1 | Phenylalanine derivatives | PAH, FPR1, VCAM1 | ITGB1 4/4885ITGA4 32/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.