Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 6/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 2/20 | 0.32 |
| ▸ | HTR1B | P28222 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6689482 | 0.89 | CYP2C9 (0.35) | LMNACNR2CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL6698686 | 0.85 | ABCB1 (0.40) | LMNATP53KMT2AMAPT | |
| SCHEMBL6688607 | 0.84 | ALDH1A1 (0.35) | LMNACNR2CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL6697773 | 0.83 | LMNA (0.35) | LMNACNR2CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL6689067 | 0.80 | HRH3 (0.35) | LMNAHRH3MEN1ALDH1A1KMT2A | |
| SCHEMBL6694261 | 0.79 | LMNA (0.40) | LMNAHRH3TP53ALDH1A1BCHE | |
| SCHEMBL6691237 | 0.78 | CYP1A2 (0.35) | CYP2C9CYP2C19CYP1A2TP53KMT2A | |
| SCHEMBL6691800 | 0.73 | ABCB1 (0.40) | LMNAKMT2AMAPT | |
| SCHEMBL6693809 | 0.73 | HRH3 (0.38) | LMNAHRH3MEN1ALDH1A1KMT2A | |
| SCHEMBL6693776 | 0.73 | SMN1; SMN2 (0.38) | LMNACYP2C9CYP2C19CYP1A2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869016-B1 | Pneumatic radial tires | BRIDGESTONE CORP (JP) | 2004-03-03 | — | — | EP | disclosed |
| US-6336486-B1 | Pneumatic radical tire having cap base tread | BRIDGESTONE CORPORATION (JP) | 2002-01-08 | — | — | US | disclosed |
| EP-0869016-A2 | Pneumatic radial tires | Bridgestone Corporation (JP) | 1998-10-07 | — | — | EP | disclosed |
| EP-0854168-A1 | Rubber composition | Bridgestone Corporation (JP) | 1998-07-22 | — | — | EP | disclosed |