Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.63 |
| ▸ | ACACB | O00763 | 1/20 | 0.61 |
| ▸ | ACACA | Q13085 | 1/20 | 0.61 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.57 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.57 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | CPT2 | P23786 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | ARG2 | P78540 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28606082 | 1.00 | ACLY (0.63) | ACLYACACBACACACYP4F2CYP4A11 | |
| SCHEMBL6699125 | 1.00 | ACLY (0.63) | ACLYACACBACACACYP4F2CYP4A11 | |
| SCHEMBL28369873 | 1.00 | ACLY (0.63) | ACLYACACBACACACYP4F2CYP4A11 | |
| SCHEMBL8571217 | 0.98 | ACLY (0.59) | ACLYACACBACACACYP4F2CYP4A11 | |
| SCHEMBL5075315 | 0.95 | ACLY (0.56) | ACLYACACBACACACYP4F2CYP4A11 | |
| SCHEMBL9837397 | 0.93 | ACLY (0.54) | ACLYACACBACACACYP4F2CYP4A11 | |
| 1,6-Hexanediol SCHEMBL11319932 | 0.92 | ACLY (0.55) | ACLYACACBACACACYP4F2CYP4A11 | |
| SCHEMBL5528331 | 0.90 | ACLY (0.74) | ACLYACACBACACACYP4F2CYP4A11 | |
| SCHEMBL1836313 | 0.90 | ACLY (0.74) | ACLYACACBACACACYP4F2CYP4A11 | |
| SCHEMBL20474799 | 0.90 | ACLY (0.74) | ACLYACACBACACACYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101129349-A | Carboxylic acids and derivatives thereof and pharmaceutical compositions containing them | YISSUM RES DEV CO (IL) | 2008-02-27 | — | — | CN | claimed |
| US-20040171585-A1 | Carboxylic acids and derivatives thereof and pharmaceutical compositions containing them | BAR-TANA JACOB (IL) | 2004-09-02 | — | — | US | claimed |
| US-20040171688-A1 | Carboxylic acids and derivatives thereof and pharmaceutical compositions containing them | BAR-TANA JACOB (IL) | 2004-09-02 | — | — | US | claimed |
| US-20020037876-A1 | Carboxylic acids and derivatives thereof and pharmaceutical compositions containing them | YISSUM RESEARCH DEVELOPMENT COMPANY OF HEBREW UNIVERSITY OF JERUSALEM | 2002-03-28 | — | — | US | claimed |
| CN-1261274-A | carboxylic acids and derivatives thereof and pharmaceutical compositions containing them | YISSUM RES DEV CO (IL) | 2000-07-26 | — | — | CN | claimed |
| CN-101129349-A | Carboxylic acids and derivatives thereof and pharmaceutical compositions containing them | YISSUM RES DEV CO (IL) | 2008-02-27 | — | — | CN | disclosed |
| US-20040171585-A1 | Carboxylic acids and derivatives thereof and pharmaceutical compositions containing them | BAR-TANA JACOB (IL) | 2004-09-02 | — | — | US | disclosed |
| US-20040171688-A1 | Carboxylic acids and derivatives thereof and pharmaceutical compositions containing them | BAR-TANA JACOB (IL) | 2004-09-02 | — | — | US | disclosed |
| US-20020037876-A1 | Carboxylic acids and derivatives thereof and pharmaceutical compositions containing them | YISSUM RESEARCH DEVELOPMENT COMPANY OF HEBREW UNIVERSITY OF JERUSALEM | 2002-03-28 | — | — | US | disclosed |
| US-6303653-B1 | THERAPY OF HEPATOCYTE NUCLEAR FACTOR-4.ALPHA..SUP.1 (HNF-4) MEDIATED DISEASE BY ADMINISTERING CARBOXYLIC ACID OR ITS DERIVATIVE WHICH INHIBITS HNF-4 CONTROLLED TRANSCRIPTION | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2001-10-16 | — | — | US | disclosed |
| CN-1261274-A | carboxylic acids and derivatives thereof and pharmaceutical compositions containing them | YISSUM RES DEV CO (IL) | 2000-07-26 | — | — | CN | disclosed |
| EP-1001755-A2 | CARBOXYLIC ACIDS AND DERIVATIVES THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999000116-A2 | CARBOXYLIC ACIDS AND DERIVATIVES THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (US) | 1999-01-07 | — | — | WO | disclosed |