SCHEMBL6692326

SCHEMBL6692326

C=C(C)C(=O)OCCC[SiH](OC)OC.C=C(C)C(=O)OCCC[Si](C)(OC(C)C)OC(C)C

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.39
POLB P06746 1/20 0.34
APEX1 P27695 1/20 0.34
HTT P42858 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
THRB P10828 1/20 0.34
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL137902 0.88 TSHR (0.49) TSHRPOLBAPEX1HTTTDP1
SCHEMBL136943 0.82 TSHR (0.55) TSHRPOLBAPEX1HTTTDP1
SCHEMBL27951178 0.81 TSHR (0.45) TSHRPOLBAPEX1HTTTDP1
SCHEMBL2552791 0.80 TSHR (0.47) TSHRPOLBAPEX1HTTTDP1
SCHEMBL2246480 0.79 TSHR (0.47) TSHRPOLBAPEX1HTTTDP1
SCHEMBL133182 0.78 TSHR (0.50) TSHRPOLBAPEX1HTTTDP1
SCHEMBL35127 0.78 TSHR (0.58) TSHRPOLBAPEX1HTTTDP1
SCHEMBL10991089 0.78 TSHR (0.47) TSHRPOLBAPEX1HTTTDP1
SCHEMBL25812302 0.77 TSHR (0.46) TSHRPOLBAPEX1HTTTDP1
SCHEMBL28617940 0.77 TSHR (0.49) TSHRPOLBAPEX1HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6790909-B2 INITIATOR FUNCTIONS SUITABLE FOR CATIONIC POLYMERIZATION INTO THE MACROINITIATOR. EXAMPLES OF SUCH INTERESTING INITIATOR FUNCTIONS ARE GROUPS CONTAINING HALOGEN OR SULFONYL CHLORIDE BASF AKTIENGESELLSCHAFT (DE) 2004-09-14 US disclosed
US-20040024145-A1 Graft copolymers, their preparation and their use BASF AKTIENGESELLSCHAFT (DE) 2004-02-05 US disclosed