Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 11/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.57 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4350863 | 0.84 | SLC6A3 (0.65) | SLC6A3SLC6A2SLC6A4FGF23PTGS2 | |
| SCHEMBL1752157 | 0.84 | SLC6A3 (0.65) | SLC6A3SLC6A2SLC6A4FGF23PTGS2 | |
| SCHEMBL4350872 | 0.84 | SLC6A3 (0.65) | SLC6A3SLC6A2SLC6A4FGF23PTGS2 | |
| SCHEMBL1752156 | 0.84 | SLC6A3 (0.65) | SLC6A3SLC6A2SLC6A4FGF23PTGS2 | |
| SCHEMBL1751614 | 0.84 | SLC6A3 (0.65) | SLC6A3SLC6A2SLC6A4FGF23PTGS2 | |
| SCHEMBL1751676 | 0.84 | SLC6A3 (0.65) | SLC6A3SLC6A2SLC6A4FGF23PTGS2 | |
| SCHEMBL4198945 | 0.81 | SLC6A3 (0.64) | SLC6A3SLC6A2SLC6A4ALDH1A1PTGS2 | |
| SCHEMBL17972851 | 0.81 | SLC6A3 (0.61) | SLC6A3SLC6A2SLC6A4MAPTSMN1; SMN2 | |
| SCHEMBL1751726 | 0.80 | SLC6A3 (0.60) | SLC6A3SLC6A2SLC6A4FGF23PTGS2 | |
| SCHEMBL4282335 | 0.78 | SLC6A3 (0.64) | SLC6A3SLC6A2SLC6A4PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1472226-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003045921-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-06-05 | — | — | WO | disclosed |