Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 1/20 | 0.48 |
| ▸ | GRM6 | O15303 | 1/20 | 0.48 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.48 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 5/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 5/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 4/20 | 0.43 |
| ▸ | ACE | P12821 | 3/20 | 0.43 |
| ▸ | CPA1 | P15085 | 3/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6695868 | 1.00 | GRM8 (0.48) | GRM8GRM6GRM2GRM3ITGB1 | |
| SCHEMBL6695079 | 0.92 | GRM8 (0.47) | GRM8GRM6GRM2GRM3ITGB1 | |
| Hydrochloric Acid SCHEMBL6696807 | 0.84 | LMNA (0.48) | GRM8GRM6GRM2GRM3ITGB1 | |
| SCHEMBL6702212 | 0.81 | GRM2 (0.50) | GRM8GRM6GRM2GRM3SLC1A2 | |
| SCHEMBL6696390 | 0.78 | SLC1A2 (0.54) | GRM8GRM6GRM2GRM3SLC1A2 | |
| SCHEMBL6695863 | 0.76 | GRM2 (0.47) | GRM8GRM6GRM2GRM3SLC1A2 | |
| SCHEMBL6696171 | 0.75 | SLC1A2 (0.59) | GRM8GRM6GRM2GRM3SLC1A2 | |
| SCHEMBL16294576 | 0.75 | ITGB1 (0.60) | ITGB1ITGA4ALDH1A1MME | |
| SCHEMBL6694165 | 0.73 | SLC1A2 (0.56) | GRM8GRM6GRM2GRM3SLC1A2 | |
| SCHEMBL9716658 | 0.69 | LMNA (0.82) | LMNATDP1POLBALDH1A1MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040176459-A1 | Prodrugs of excitatory amino acids | ELI LILLY AND COMPANY | 2004-09-09 | — | — | US | claimed |
| US-20040176459-A1 | Prodrugs of excitatory amino acids | ELI LILLY AND COMPANY | 2004-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176459-A1 | Prodrugs of excitatory amino acids | SLC1A2, SLC1A1, SLC1A3 | GRM8 44/4885GRM6 27/4885GRM2 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.