Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.92 |
| ▸ | MAPT | P10636 | 6/20 | 0.92 |
| ▸ | LMNA | P02545 | 5/20 | 0.92 |
| ▸ | HTT | P42858 | 2/20 | 0.92 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.92 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.72 |
| ▸ | MEN1 | O00255 | 3/20 | 0.72 |
| ▸ | POLB | P06746 | 3/20 | 0.72 |
| ▸ | TSHR | P16473 | 3/20 | 0.72 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.72 |
| ▸ | XBP1 | P17861 | 1/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.45 |
| ▸ | PRNP | P04156 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14366836 | 0.96 | ALDH1A1 (1.00) | ALDH1A1MAPTLMNAHTTHIF1A | |
| SCHEMBL14366837 | 0.92 | MAPT (0.82) | ALDH1A1MAPTLMNAHTTHIF1A | |
| SCHEMBL6690424 | 0.91 | ALDH1A1 (0.79) | ALDH1A1MAPTLMNAHTTHIF1A | |
| SCHEMBL14366818 | 0.86 | MAPT (0.71) | ALDH1A1MAPTLMNAHTTHIF1A | |
| SCHEMBL6694656 | 0.85 | MAPT (0.71) | ALDH1A1MAPTLMNAHTTHIF1A | |
| SCHEMBL5606330 | 0.84 | ALDH1A1 (1.00) | ALDH1A1MAPTLMNAHTTHIF1A | |
| SCHEMBL6692642 | 0.83 | MAPT (0.68) | ALDH1A1MAPTLMNAHTTHIF1A | |
| SCHEMBL6691891 | 0.83 | MAPT (0.68) | ALDH1A1MAPTLMNAHTTHIF1A | |
| SCHEMBL6686783 | 0.83 | MAPT (0.68) | ALDH1A1MAPTLMNAHTTHIF1A | |
| SCHEMBL14366838 | 0.83 | ALDH1A1 (0.83) | ALDH1A1MAPTLMNAHTTHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004096808-A1 | TRIAZINE COMPOUNDS AND THEIR USE | DE NOVO PHARMACEUTICALS LIMITED (GB) | 2004-11-11 | — | — | WO | claimed |
| WO-2004096808-A1 | TRIAZINE COMPOUNDS AND THEIR USE | DE NOVO PHARMACEUTICALS LIMITED (GB) | 2004-11-11 | — | — | WO | disclosed |