Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 1.00 |
| ▸ | TSHR | P16473 | 6/20 | 1.00 |
| ▸ | LMNA | P02545 | 4/20 | 1.00 |
| ▸ | POLB | P06746 | 4/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 4/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | XBP1 | P17861 | 1/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 9/20 | 0.79 |
| ▸ | HTT | P42858 | 1/20 | 0.79 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.79 |
| ▸ | TP53 | P04637 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14366838 | 0.91 | ALDH1A1 (0.83) | ALDH1A1TSHRLMNAPOLBMAPK1 | |
| SCHEMBL6688843 | 0.90 | ALDH1A1 (0.82) | ALDH1A1TSHRLMNAPOLBMAPK1 | |
| SCHEMBL14366845 | 0.89 | ALDH1A1 (0.80) | ALDH1A1TSHRLMNAPOLBMAPK1 | |
| SCHEMBL14366843 | 0.89 | ALDH1A1 (0.80) | ALDH1A1TSHRLMNAPOLBMAPK1 | |
| SCHEMBL14366836 | 0.88 | ALDH1A1 (1.00) | ALDH1A1TSHRLMNAPOLBMAPK1 | |
| SCHEMBL6690424 | 0.88 | ALDH1A1 (0.79) | ALDH1A1TSHRLMNAPOLBMAPK1 | |
| SCHEMBL14366841 | 0.88 | LMNA (0.79) | ALDH1A1TSHRLMNAPOLBMAPK1 | |
| SCHEMBL6692102 | 0.87 | ALDH1A1 (0.77) | ALDH1A1TSHRLMNAPOLBMAPK1 | |
| SCHEMBL14366839 | 0.87 | ALDH1A1 (0.76) | ALDH1A1TSHRLMNAPOLBMAPK1 | |
| SCHEMBL14366840 | 0.86 | ALDH1A1 (0.76) | ALDH1A1TSHRLMNAPOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004096808-A1 | TRIAZINE COMPOUNDS AND THEIR USE | DE NOVO PHARMACEUTICALS LIMITED (GB) | 2004-11-11 | — | — | WO | claimed |
| US-20070269420-A1 | Compounds, Compositions and Methods for Treatment and Prophylaxis of Hepatitis C Viral Infections and Associated Diseases | VIROPHARMA INCORPORATED | 2007-11-22 | — | — | US | disclosed |
| US-20070269420-A1 | Compounds, Compositions and Methods for Treatment and Prophylaxis of Hepatitis C Viral Infections and Associated Diseases | VIROPHARMA INCORPORATED | 2007-11-22 | — | — | US | disclosed |
| US-20070269420-A1 | Compounds, Compositions and Methods for Treatment and Prophylaxis of Hepatitis C Viral Infections and Associated Diseases | VIROPHARMA INCORPORATED | 2007-11-22 | — | — | US | disclosed |
| WO-2004096808-A1 | TRIAZINE COMPOUNDS AND THEIR USE | DE NOVO PHARMACEUTICALS LIMITED (GB) | 2004-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070269420-A1 | Compounds, Compositions and Methods for Treatment and Prophylaxis of Hepatitis C Viral Infections and Associated Diseases | HAVCR2, FABP1, LIPC | ALDH1A1 971/4885TSHR 4657/4885LMNA 1671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.