Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 10/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 8/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | MC4R | P32245 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CLK1 | P49759 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | STAT6 | P42226 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6691958 | 0.89 | STAT6 (0.46) | SYKMAPTSMN1; SMN2STAT6PDE4B | |
| SCHEMBL6705299 | 0.88 | STAT6 (0.45) | SYKMAPTSMN1; SMN2PTK2BSTAT6 | |
| SCHEMBL6690706 | 0.85 | SYK (0.49) | SYKSTAT6PDE4B | |
| SCHEMBL6696056 | 0.84 | SYK (0.68) | SYKMAPTLMNAGAASMN1; SMN2 | |
| SCHEMBL6695716 | 0.79 | SYK (0.53) | SYKMAPTLMNAGAASTAT6 | |
| SCHEMBL6695293 | 0.79 | PDE4B (0.54) | SYKPTK2BSTAT6PDE4B | |
| SCHEMBL6701139 | 0.78 | PDE4B (0.53) | SYKPTK2BSTAT6PDE4B | |
| Hydrochloric Acid SCHEMBL6697409 | 0.77 | PDE4B (0.52) | SYKPTK2BSTAT6PDE4B | |
| SCHEMBL5381175 | 0.77 | AURKA (0.47) | MAPTLMNAGAASMN1; SMN2TDP1 | |
| SCHEMBL6696018 | 0.71 | STAT6 (0.44) | SYKMAPTLMNAHTTSTAT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108068-A2 | 4-[4-(4-MORPHOLINO)ANILINO]PYRIMIDINE DERIVATIVES, METHOD FOR PREPARING THEREOF AND ANTIVIRAL PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | B & C BIOPHARM CO., LTD. (KR) | 2004-12-16 | — | — | WO | disclosed |