Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT6 | P42226 | 6/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.43 |
| ▸ | SYK | P43405 | 4/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6695293 | 0.79 | PDE4B (0.54) | STAT6PDE4BSYKPKMYT1BTK | |
| SCHEMBL6701139 | 0.78 | PDE4B (0.53) | STAT6PDE4BSYKPKMYT1BTK | |
| SCHEMBL6696056 | 0.78 | SYK (0.68) | SYKALDH1A1MAPTHTTLMNA | |
| SCHEMBL6695716 | 0.78 | SYK (0.53) | STAT6PDE4BSYKPKMYT1BTK | |
| Hydrochloric Acid SCHEMBL6697409 | 0.78 | PDE4B (0.52) | STAT6PDE4BSYKPKMYT1BTK | |
| SCHEMBL6690699 | 0.73 | SYK (0.47) | STAT6PDE4BSYKPKMYT1BTK | |
| SCHEMBL6691958 | 0.73 | STAT6 (0.46) | STAT6PDE4BSYKPKMYT1BTK | |
| SCHEMBL6705299 | 0.72 | STAT6 (0.45) | STAT6PDE4BSYKPKMYT1BTK | |
| SCHEMBL6692523 | 0.71 | SYK (0.49) | STAT6PDE4BSYKMAPTHTT | |
| SCHEMBL31357058 | 0.71 | SYK (0.52) | STAT6PDE4BSYKPKMYT1BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108068-A2 | 4-[4-(4-MORPHOLINO)ANILINO]PYRIMIDINE DERIVATIVES, METHOD FOR PREPARING THEREOF AND ANTIVIRAL PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | B & C BIOPHARM CO., LTD. (KR) | 2004-12-16 | — | — | WO | disclosed |