Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT6 | P42226 | 2/20 | 0.45 |
| ▸ | SYK | P43405 | 6/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PKMYT1 | Q99640 | 2/20 | 0.43 |
| ▸ | INSR | P06213 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.43 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6691958 | 0.91 | STAT6 (0.46) | STAT6SYKPDE4BMAPTPKMYT1 | |
| SCHEMBL6690706 | 0.90 | SYK (0.49) | STAT6SYKPDE4BALK | |
| SCHEMBL6692523 | 0.88 | SYK (0.49) | STAT6SYKPDE4BMAPTPTK2B | |
| SCHEMBL6695293 | 0.81 | PDE4B (0.54) | STAT6SYKPDE4BPKMYT1INSR | |
| SCHEMBL6701139 | 0.80 | PDE4B (0.53) | STAT6SYKPDE4BPKMYT1INSR | |
| SCHEMBL6695716 | 0.79 | SYK (0.53) | STAT6SYKPDE4BMAPTPKMYT1 | |
| Hydrochloric Acid SCHEMBL6697409 | 0.79 | PDE4B (0.52) | STAT6SYKPDE4BPKMYT1INSR | |
| SCHEMBL6696056 | 0.78 | SYK (0.68) | SYKMAPTPTK2BSMN1; SMN2 | |
| SCHEMBL5815015 | 0.76 | AURKA (0.47) | STAT6MAPTIGF1RSMN1; SMN2 | |
| SCHEMBL14067297 | 0.74 | LRRK2 (0.48) | PDE4BCCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108068-A2 | 4-[4-(4-MORPHOLINO)ANILINO]PYRIMIDINE DERIVATIVES, METHOD FOR PREPARING THEREOF AND ANTIVIRAL PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | B & C BIOPHARM CO., LTD. (KR) | 2004-12-16 | — | — | WO | disclosed |