SCHEMBL6692629

SCHEMBL6692629

O=C1C=CC(c2ccc(C(=O)O)cc2)=CC1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.43
TSHR P16473 1/20 0.43
BCL2L1 Q07817 1/20 0.41
BAD Q92934 1/20 0.41
CA12 O43570 5/20 0.41
CA1 P00915 5/20 0.41
CA9 Q16790 5/20 0.41
CA2 P00918 4/20 0.41
CA14 Q9ULX7 4/20 0.41
SRD5A2 P31213 1/20 0.39
RXRA P19793 4/20 0.39
RXRB P28702 4/20 0.39
KDM4E B2RXH2 2/20 0.39
RXRG P48443 1/20 0.39
LMNA P02545 1/20 0.39
HSD17B10 Q99714 1/20 0.39
ALDH1A1 P00352 2/20 0.38
DDAH1 O94760 1/20 0.38
CA3 P07451 1/20 0.38
TYR P14679 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalic Acid SCHEMBL6535714 0.72 RXRA (0.40) TP53TSHRCA12CA1CA9
SCHEMBL2250920 0.69 TSHR (0.40) TP53TSHRBCL2L1BADCA12
SCHEMBL14018385 0.68 TSHR (0.80) TP53TSHRBCL2L1BADCA12
SCHEMBL69873 0.68 TSHR (0.80) TP53TSHRBCL2L1BADCA12
SCHEMBL2637326 0.68 TSHR (0.80) TP53TSHRBCL2L1BADCA12
Terephthalic Acid SCHEMBL9577834 0.68 TSHR (0.80) TP53TSHRBCL2L1BADCA12
SCHEMBL6667036 0.66 TSHR (0.75) TP53TSHRBCL2L1BADCA12
Fluoride SCHEMBL20513068 0.66 TSHR (0.75) TP53TSHRBCL2L1BADCA12
Hydrochloric Acid SCHEMBL1681911 0.66 TSHR (0.75) TP53TSHRBCL2L1BADCA12
SCHEMBL21808797 0.66 TSHR (0.75) TP53TSHRBCL2L1BADCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004094502-A1 AMORPHOUS WHOLLY AROMATIC POLYESTERAMIDE AND COMPOSITION COMPRISING THE SAME POLYPLASTICS CO., LTD. (JP) 2004-11-04 WO disclosed
EP-0102719-A1 Wholly aromatic polyesters comprising 6-oxy-2-naphthoyl moiety and 4-oxy-4'-carboxy biphenyl moiety CELANESE CORPORATION (US) 1984-03-14 EP disclosed
EP-0102719-A1 Wholly aromatic polyesters comprising 6-oxy-2-naphthoyl moiety and 4-oxy-4'-carboxy biphenyl moiety CELANESE CORPORATION (US) 1984-03-14 EP disclosed
EP-0102719-A1 Wholly aromatic polyesters comprising 6-oxy-2-naphthoyl moiety and 4-oxy-4'-carboxy biphenyl moiety CELANESE CORPORATION (US) 1984-03-14 EP disclosed
US-4431770-A Wholly aromatic polyester comprising 4-oxy-4'-carboxybiphenyl moiety which is capable of forming an anisotropic melt phase CELANESE CORPORATION (US) 1984-02-14 US disclosed
US-4431770-A Wholly aromatic polyester comprising 4-oxy-4'-carboxybiphenyl moiety which is capable of forming an anisotropic melt phase CELANESE CORPORATION (US) 1984-02-14 US disclosed
US-4431770-A Wholly aromatic polyester comprising 4-oxy-4'-carboxybiphenyl moiety which is capable of forming an anisotropic melt phase CELANESE CORPORATION (US) 1984-02-14 US disclosed