Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 3/20 | 0.38 |
| ▸ | F10 | P00742 | 3/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.38 |
| ▸ | F7 | P08709 | 3/20 | 0.38 |
| ▸ | MRGPRX1 | Q96LB2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6694608 | 0.88 | BCHE (0.44) | BCHEPDE2ANPC1PKMRAB9A | |
| SCHEMBL6694007 | 0.85 | BCHE (0.44) | BCHEFFAR4NPC1PKMRAB9A | |
| SCHEMBL6694003 | 0.85 | BCHE (0.44) | BCHEFFAR4NPC1PKMRAB9A | |
| SCHEMBL6694094 | 0.84 | PTPRZ1 (0.52) | — | |
| SCHEMBL6693062 | 0.82 | MAOB (0.45) | FFAR4NPC1PKMRAB9ANTRK1 | |
| SCHEMBL6693067 | 0.82 | MAOB (0.45) | FFAR4NPC1PKMRAB9ANTRK1 | |
| SCHEMBL6688875 | 0.81 | MTNR1A (0.52) | BCHENPC1PKMRAB9ACSF1R | |
| SCHEMBL6690103 | 0.80 | ATM (0.47) | FFAR4NPC1PKMRAB9ANTRK1 | |
| SCHEMBL6685506 | 0.80 | PDCD1 (0.53) | BCHEFFAR4NPC1PKMRAB9A | |
| SCHEMBL6690101 | 0.80 | ATM (0.47) | FFAR4NPC1PKMRAB9ANTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087125-A1 | AMINO ACID DERIVATIVES AS INHIBITORS OF MAMMALIAN SODIUM CHANNELS | IONIX PHARMACEUTICALS LIMITED (GB) | 2004-10-14 | — | — | WO | disclosed |