Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 5/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | BLM | P54132 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1491624 | 0.94 | FAAH (0.47) | CHRM1CHRM4CHRM5CHRM3CHRM2 | |
| SCHEMBL28986531 | 0.94 | FAAH (0.44) | CHRM1CHRM4CHRM5CHRM3CHRM2 | |
| Hydrochloric Acid SCHEMBL17707257 | 0.92 | FAAH (0.46) | CHRM1CHRM4CHRM5CHRM3CHRM2 | |
| SCHEMBL28841763 | 0.92 | FAAH (0.49) | CHRM1CHRM4CHRM5CHRM3CHRM2 | |
| SCHEMBL28841740 | 0.84 | CTSL (0.48) | CHRM1CHRM4CHRM5CHRM3CHRM2 | |
| SCHEMBL28841789 | 0.84 | CTSL (0.48) | CHRM1CHRM4CHRM5CHRM3CHRM2 | |
| SCHEMBL4681333 | 0.79 | KMT2A (0.52) | LMNATHRBHSD17B10MEN1KMT2A | |
| SCHEMBL158072 | 0.79 | KMT2A (0.52) | LMNATHRBHSD17B10MEN1KMT2A | |
| SCHEMBL29033348 | 0.79 | TDP1 (0.50) | LMNATHRBHSD17B10MEN1KMT2A | |
| SCHEMBL4526290 | 0.79 | KMT2A (0.52) | LMNATHRBHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043911-A2 | N-CYCLOALKYLGLYCINES AS HIV PROTEASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-05-27 | — | — | WO | disclosed |