Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | ATM | Q13315 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6692852 | 1.00 | TSHR (0.67) | TSHRHCAR2CYP3A4TDP1ATM | |
| SCHEMBL972676 | 0.98 | TSHR (0.69) | TSHRHCAR2CYP3A4TDP1ATM | |
| SCHEMBL790118 | 0.98 | TSHR (0.69) | TSHRHCAR2CYP3A4TDP1ATM | |
| SCHEMBL242750 | 0.98 | TSHR (0.69) | TSHRHCAR2CYP3A4TDP1ATM | |
| SCHEMBL242751 | 0.98 | TSHR (0.69) | TSHRHCAR2CYP3A4TDP1ATM | |
| Ammonia Solution, Strong SCHEMBL9436306 | 0.97 | TSHR (0.67) | TSHRHCAR2CYP3A4TDP1ATM | |
| SCHEMBL9456765 | 0.97 | TSHR (0.67) | TSHRHCAR2CYP3A4TDP1ATM | |
| SCHEMBL9456754 | 0.97 | TSHR (0.67) | TSHRHCAR2CYP3A4TDP1ATM | |
| Hydrochloric Acid SCHEMBL4611985 | 0.97 | TSHR (0.67) | TSHRHCAR2CYP3A4TDP1ATM | |
| SCHEMBL9436436 | 0.97 | TSHR (0.67) | TSHRHCAR2CYP3A4TDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0987295-B1 | Combination of an organothio compound and a zinc mercapto ester as heat stabilizer in PVC processing | MORTON INT INC (US) | 2004-07-21 | — | — | EP | disclosed |
| US-6462116-B2 | POLYVINYL CHLORIDE(PVC), OR OTHER HALOPOLYMERS; 2-MERCAPTOETHANOL AND ZINC BIS(2-ETHYLHEXYLTHIOGLYCOLATE) FOR EXAMPLE; ELIMINATES ZINC BURN DURING PROCESSING | MORTON INTERNATIONAL, INC. | 2002-10-08 | — | — | US | disclosed |
| US-20010036987-A1 | Combination of an organothio compound and a zinc mercapto ester as a heat stabilizer in PVC processing | MORTON INTERNATIONAL, INC. | 2001-11-01 | — | — | US | disclosed |
| EP-0987295-A1 | Combination of an organothio compound and a zinc mercapto ester as heat stabilizer in PVC processing | MORTON INTERNATIONAL, INC. (US) | 2000-03-22 | — | — | EP | disclosed |
| US-5808165-A | CLAISEN CONDENSATION | RHONE-POULENC CHIMIE (FR) | 1998-09-15 | — | — | US | disclosed |
| US-5475145-A | Odorless, nontoxic liquid mixtures for stabilizing polyvinyl chloride and other halopolymers | RHONE-POULENC (FR) | 1995-12-12 | — | — | US | disclosed |
| US-5278218-A | Heat resistance | RHONE-POULENC CHIMIE (FR) | 1994-01-11 | — | — | US | disclosed |
| US-5241028-A | Monomer is at least 20% neutralized, one step process | THE DOW CHEMICAL COMPANY (US) | 1993-08-31 | — | — | US | disclosed |
| US-5234981-A | HALOGENATED POLYMER COMPOSITIONS STABILIZED WITH THE AID OF AN INORGANIC ADDITIVE | RHONE-POULENC CHIMIE (FR) | 1993-08-10 | — | — | US | disclosed |
| US-5200444-A | Polymer matrices heat and light stabilized with novel benzophenone/1,4-dihydropyridine compounds | RHONE-POULENC CHIMIE (FR) | 1993-04-06 | — | — | US | disclosed |
| US-5194470-A | Nonyellowing polymer compositions for heat stability | RHONE-POULENC CHIMIE (FR) | 1993-03-16 | — | — | US | disclosed |
| US-5143959-A | Mixture of dawsonite, hydrotalcite, polysiloxane and organometallic compound; heat resistant | RHONE-POULENC CHIMIE (FR) | 1992-09-01 | — | — | US | disclosed |
| US-5124456-A | HINDERED AMINE-SUBSTITUTED DIHYDROPYRIDINES AND HEAT/LIGHT STABILIZATION OF POLYMER SUBSTRATES THEREWITH | RHONE-POULENC CHIMIE (FR) | 1992-06-23 | — | — | US | disclosed |
| US-5070128-A | ORGANOZINC AND ORGANOALKALINE EARTH COMPOUNDS, SODIUM BETA-DIK ETONATE AS STABILIZERS | RHONE-POULENC CHIMIE (FR) | 1991-12-03 | — | — | US | disclosed |
| US-5034533-A | Polyesterether copolymers as stabilizers for polymers | RHONE-POULENC CHIMIE (FR) | 1991-07-23 | — | — | US | disclosed |