Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.62 |
| ▸ | PAM | P19021 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PRKCA | P17252 | 1/20 | 0.47 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.47 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.47 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL6368814 | 0.98 | DGKA (0.64) | DGKAPAMTSHRMAPTCYP1A2 | |
| Sulfuric Acid SCHEMBL7924258 | 0.98 | DGKA (0.64) | DGKAPAMTSHRMAPTCYP1A2 | |
| Sulfuric Acid SCHEMBL28105327 | 0.96 | DGKA (0.62) | DGKAPAMTSHRMAPTCYP1A2 | |
| Sulfuric Acid SCHEMBL9776635 | 0.96 | DGKA (0.62) | DGKAPAMTSHRMAPTCYP1A2 | |
| Sulfuric Acid SCHEMBL28124120 | 0.96 | DGKA (0.61) | DGKAPAMTSHRMAPTCYP1A2 | |
| Ethyl Tetradecanoate SCHEMBL31277626 | 0.92 | DGKA (0.62) | DGKAPAMTSHRMAPTCYP1A2 | |
| Ammonia Solution, Strong SCHEMBL11147784 | 0.92 | DGKA (0.72) | DGKAPAMTSHRMAPTCYP1A2 | |
| Ammonia Solution, Strong SCHEMBL21219078 | 0.92 | DGKA (0.72) | DGKAPAMTSHRMAPTCYP1A2 | |
| Ammonia Solution, Strong SCHEMBL484756 | 0.92 | DGKA (0.72) | DGKAPAMTSHRMAPTCYP1A2 | |
| Ammonia Solution, Strong SCHEMBL27880730 | 0.92 | DGKA (0.72) | DGKAPAMTSHRMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9364420-B2 | Hair conditioning compositions | KAO USA INC. (US) | 2016-06-14 | — | — | US | disclosed |
| EP-2948127-A2 | HAIR AND SKIN CONDITIONING COMPOSITIONS | Kao Corporation (JP) | 2015-12-02 | — | — | EP | disclosed |
| WO-2014114975-A2 | HAIR AND SKIN CONDITIONING COMPOSITIONS | KAO CORPORATION (JP) | 2014-07-31 | — | — | WO | disclosed |
| US-20130164240-A1 | HAIR CONDITIONING COMPOSITIONS | KAO CORPORATION (JP) | 2013-06-27 | — | — | US | disclosed |
| US-20130039873-A1 | HAIR AND SKIN CONDITIONING COMPOSITIONS | KAO CORPORATION (JP) | 2013-02-14 | — | — | US | disclosed |
| WO-2012024364-A2 | HAIR AND SKIN CONDITIONING COMPOSITIONS | KAO CORPORATION (JP) | 2012-02-23 | — | — | WO | disclosed |